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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-11</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая медицина</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical medicine</subject></subj-group></article-categories><title-group><article-title>ГРИБКОВАЯ АЛЛЕРГИЯ – АЭРОБИОЛОГИЧЕСКИЕ АСПЕКТЫ В Г. САМАРЕ</article-title><trans-title-group xml:lang="en"><trans-title>FUNGAL ALLERGY: AEROBIOLOGICAL ASPECTS IN SAMARA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазоха</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazokha</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры внутренних болезней, </p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Манжос</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Manzhos</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующий кафедрой внутренних болезней, </p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры внутренних болезней, </p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хабибулина</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Khabibulina</surname><given-names>L. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, доцен кафедры морфологии и патологии, </p><p>Самара</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Власова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vlasova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат биологических наук, доцент кафедры экологии, ботаники и охраны природы, </p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кавеленова</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kavelenova</surname><given-names>L. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор биологических наук, профессор, заведующий кафедрой экологии, ботаники и охраны природы, </p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зацепин</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zatsepin</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры внутренних болезней, </p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Краснова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasnova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студент 4 курса,</p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Частное учреждение образовательная организация высшего образования «Медицинский университет «Реавиз»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Private Institution of Higher Education ‘Medical University ‘Reaviz’</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Частное учреждение образовательная организация высшего образования «Московский медицинский университет «Реавиз»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Private Institution of Higher Education ‘Moscow Medical University ‘Reaviz’</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Самарский национальный исследовательский университет имени академика С.П. Королева»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Autonomous Institution of Higher Education ‘S.P. Korolev Samara National Research University’</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>24</day><month>11</month><year>2020</year></pub-date><volume>0</volume><issue>2</issue><fpage>6</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мазоха К.С., Манжос М.В., Жукова Н.Н., Хабибулина Л.Р., Власова Н.В., Кавеленова Л.М., Зацепин А.С., Краснова А.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Мазоха К.С., Манжос М.В., Жукова Н.Н., Хабибулина Л.Р., Власова Н.В., Кавеленова Л.М., Зацепин А.С., Краснова А.А.</copyright-holder><copyright-holder xml:lang="en">Mazokha K.S., Manzhos M.V., Zhukova N.N., Khabibulina L.R., Vlasova N.V., Kavelenova L.M., Zatsepin A.S., Krasnova A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/11">https://vestnik.reaviz.ru/jour/article/view/11</self-uri><abstract><p>Цель исследования – изучить динамику спорообразования плесневых грибов для прогнозирования риска обострения аллергических заболеваний в г. Самаре.</p><sec><title>Материалы и методы</title><p>Материалы и методы. С 1 апреля по 30 сентября 2016–2019 гг. споры плесневых грибов улавливали с помощью ловушки-импактора, на предметные стекла, покрытые смесью вазелина и воска, с последующим подсчетом числа грибковых спор и определением их принадлежности к различным таксонам.</p></sec><sec><title>Результаты</title><p>Результаты. Вегетационный период плесневых грибов в г. Самаре составил в среднем 164 дня. Были идентифицированы споры грибов рода Cladosporium и Alternaria, которые составили 34,4 % от общего числа спор в атмосферном воздухе г. Самары. Споры грибов рода Cladosporium регистрировались в течение всего периода наблюдений, их удельный вес составил 15,3 % от общего числа грибных спор, максимальные значения были на уровне средних показателей и не превышали 960 спор/м3. Удельный вес спор рода Alternaria составил 19,1 %. Превышение пороговых концентраций спор Alternaria от 10 до 100 спор/м3 отмечено от 4 до 31 дней за месяц, более 100 спор/м3 – от 2 до 25 дней за месяц. Наибольшее суммарное среднемесячное число спор грибов рода Alternaria присутствовало в июле-сентябре, в период пыления полыни и амброзии, что может вызывать затруднение при проведении диагностики и лечении пациентов, имеющих обострения аллергических заболеваний в данный период.</p></sec><sec><title>Заключение</title><p>Заключение. Выделены основные таксоны плесневых грибов, изучена их региональная специфика, оценен риск развития аллергических заболеваний при сенсибилизации к грибам рода Alternaria и Cladosporium. Полученные данные позволят оптимизировать диагностику, лечение и профилактику аллергических заболеваний в регионе. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to analyze dynamics of sporulation of mold fungi in order to predict the risks of exacerbation of allergic diseases in Samara.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. We evaluated the concentration of fungal spores between April 1st and September 30th in 2016–2019 in the air. Mold spores were captured using an impactor trap on slides covered with a mixture of vaseline and wax with subsequent counting of spore number and their identification.</p></sec><sec><title>Results</title><p>Results. The mean vegetative period of mold fungi in Samara city was 164 days. We have identified spores of Cladosporium and Alternaria, which accounted for 34.4 % of the total number of spores in the atmospheric air of Samara. Cladosporium spores were detected during the entire observation period; their proportion was 15.3% from the total number of fungal spores, their maximum concentrations were within the normal limits and did not exceed 960 spores/m3. The proportion of Alternaria spores was 19.1%. In some periods, concentrations of Alternaria spores exceeded threshold values: the concentration between 10 and 100 spores/m3 was observed 4 to 31 days per months; the concentration above 100 spores/m3 was observed 2 to 25 days per month. The highest total monthly concentration of Alternaria spores was detected in July–September, during the period of sagebrush and ragweed pollination, which can potentially hamper the diagnosis and treatment of patients who have exacerbations of their allergic diseases in this period.</p></sec><sec><title>Conclusion</title><p>Conclusion. We have identified the main taxa of mold fungi, analyzed their regional specificity and assessed the risk of allergic diseases in individuals sensitized to Alternaria and Cladosporium species. Our findings will help to optimize the diagnosis, treatment, and prevention of allergic diseases in the region. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>аэробиология</kwd><kwd>грибковые споры</kwd><kwd>Cladosporium</kwd><kwd>Alternaria</kwd><kwd>грибковая сенсибилизация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>aerobiology</kwd><kwd>fungal spores</kwd><kwd>Cladosporium</kwd><kwd>Alternaria</kwd><kwd>fungal sensitization</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zureik M., Neukirch C, Leynaert B. et al. Sensitisation to airborne moulds and severity of asthma: cross sectional study from European Community respiratory health survey. 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