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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2024.4.MORPH.2</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-1101</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Морфология, патология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Morphology, pathology</subject></subj-group></article-categories><title-group><article-title>Сравнительный анализ микрометрических показателей в яичниках женщин юношеского, пожилого и старческого возраста</article-title><trans-title-group xml:lang="en"><trans-title>Comparative analysis of micrometric parameters in the ovaries of adolescent, elderly and senile women</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3152-8380</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баландин</surname><given-names>A. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balandin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баландин Анатолий Александрович, канд. мед. наук, доцент кафедры нормальной, топографической и клинической анатомии, оперативной хирургии</p><p>ул. Петропавловская, д. 26, г. Пермь, 614990</p></bio><bio xml:lang="en"><p>Anatoliy A. Balandin, Cand. Sci. (Med.), Associate Professor of the Department of Normal, Topographic and Clinical Anatomy, Operative Surgery</p><p>26, Petropavlovskaya St., Perm, 614990</p></bio><email xlink:type="simple">balandina_ia@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-1741-1316</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ко6елева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kobeleva</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кобелева Анна Сергеевна, старший лаборант кафедры нормальной, топографической и клинической анатомии, оперативной хирургии</p><p>ул. Петропавловская, д. 26, г. Пермь, 614990</p></bio><bio xml:lang="en"><p>Anna S. Kobeleva, Senior Laboratory Assistant of the Department of Normal, Topographic and Clinical Anatomy, Operative Surgery</p><p>26, Petropavlovskaya St., Perm, 614990</p></bio><email xlink:type="simple">a.s.kobelevaa@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4856-9066</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баландина</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balandina</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баландина Ирина Анатольевна, д-р мед. наук, профессор, заведующая кафедрой нормальной, топографической и клинической анатомии, оперативной хирургии</p><p>ул. Петропавловская, д. 26, г. Пермь, 614990</p></bio><bio xml:lang="en"><p>Irina A. Balandina, Dr. Sci. (Med.), Professor, Head of the Department of Normal, Topographic and Clinical Anatomy, Operative Surgery</p><p>26, Petropavlovskaya St., Perm, 614990</p></bio><email xlink:type="simple">balandina_ia@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0572-7594</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуляева</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gulyaeva</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гуляева Наталия Ивановна, канд. мед. наук, доцент кафедры гистологии, эмбриологии и цитологии</p><p>ул. Петропавловская, д. 26, г. Пермь, 614990</p></bio><bio xml:lang="en"><p>Natalia I. Gulyaeva, Cand. Sci. (Med.), Associate Professor of the Department of Histology, Embryology and Cytology</p><p>26, Petropavlovskaya St., Perm, 614990</p></bio><email xlink:type="simple">bizon55@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Пермский государственный медицинский университет имени академика Е.А. Вагнера</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Perm State Medical University named after Academician E.A. Wagner</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>12</day><month>10</month><year>2024</year></pub-date><volume>14</volume><issue>4</issue><fpage>14</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Баландин A.А., Ко6елева А.С., Баландина И.А., Гуляева Н.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Баландин A.А., Ко6елева А.С., Баландина И.А., Гуляева Н.И.</copyright-holder><copyright-holder xml:lang="en">Balandin A.A., Kobeleva A.S., Balandina I.A., Gulyaeva N.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/1101">https://vestnik.reaviz.ru/jour/article/view/1101</self-uri><abstract><p>Старение является процессом системным, затрагивающим все ткани организма. В данном исследовании выбор научного интереса пришёлся на парную железу, ключевую структуру женской репродуктивной системы – яичник.</p><sec><title>Цель</title><p>Цель: провести сравнительный анализ параметров толщины мозгового и коркового слоёв, а также белочной оболочки яичников у женщин в юношеском, пожилом и старческом возрасте.</p><p>Материалы и методы исследования. Проведён анализ результатов исследования 60 женщин с нормальными размерами таза и без патологии органов репродуктивной системы. I группа включала 28 погибших юношеского возраста (16–20 лет), II группа состояла из 29 погибших пожилого возраста (56–74 лет), в III группу вошли 27 погибших старческого возраста (75–90 лет). Определяли толщину мозгового и коркового слоёв, а также белочной оболочки обоих яичников в гистологических образцах.</p></sec><sec><title>Результаты</title><p>Результаты. Выявлено уменьшение показателей толщины коркового и мозгового вещества и увеличение параметров толщины белочной оболочки обоих яичников в периоде от юношеского к старческому возрасту. Толщина мозгового вещества правого яичника истончается на 3,76%, левого – на 4,46%; коркового вещества правого яичника – на 29,9%, левого – на 29,64% (p &lt; 0,01). Толщина белочной оболочки правого яичника, напротив, увеличивается на 48,23%, левого – на 50,21% (p &lt; 0,01). От пожилого возраста к старческому определяется тенденция к уменьшению толщины мозгового и коркового вещества яичника. Мозговое вещество истончается на 0,95% справа и на 0,24% слева (p &gt; 0,05), корковое вещество – на 1,5% справа и на 1,21% слева (p &gt; 0,05). При этом белочная оболочка справа становится толще на 14,08%, слева – на 13,57% (p &lt; 0,01).</p></sec><sec><title>Заключение</title><p>Заключение. Полученные результаты могут стать условным «морфологическим эталоном» для определённых возрастных норм при диагностике различных заболеваний, а также расширят представление об изменениях морфологической картины яичников женщины с возрастом.</p></sec></abstract><trans-abstract xml:lang="en"><p>Aging is a systemic process affecting all tissues of the body. In this study, the choice of scientific interest fell on the paired gland, the key structure of the female reproductive system – the ovary.</p><sec><title>Objective</title><p>Objective: to carry out a comparative analysis of the parameters of the thickness of the cerebral and cortical layers, as well as the protein membrane of the  ovaries  in women in adolescence,  the elderly and senile  age. </p></sec><sec><title>Materials and methods</title><p>Materials and methods. The analysis of the results of a study of 60 women with normal pelvic dimensions and without pathology of the reproductive system organs was carried out. Group I included 28 victims of adolescent age (16-20 years old), group II consisted of 29 elderly victims (56-74 years old), group III included 27 elderly victims (75-90 years old). The thickness of the cerebral and cortical layers, as well as the albumen of both ovaries, were determined in histological samples.</p></sec><sec><title>Results</title><p>Results. A decrease in the thickness of the cortical and medulla and an increase in the thickness parameters of the albuminous membrane of both ovaries in the period from adolescence to old age were revealed. The thickness of the medulla of the right ovary is thinned by 3.76%, the left by 4.46%; the cortical substance of the right ovary by 29.9%, the left by 29.64% (p &lt; 0,01). The thickness of the albumen of the right ovary, on the contrary, increases by 48.23%, of the left – by 50.21% (p &lt;  0,01). From old age to senile age, there is a tendency to decrease the thickness of the cerebral and cortical matter of the ovary. The medulla is thinned by 0.95% on the right and 0.24% on the left (p &gt; 0,05), the cortical substance – by 1.5% on the right and 1.21% on the left (p &gt; 0,05). At the same time, the protein shell on the right becomes thicker by 14.08%, on the left – by  13.57% (p  &lt; 0,01). </p></sec><sec><title>Conclusion</title><p>Conclusion. The results obtained can become a conditional  "morphological standard" for certain age norms in the diagnosis of various diseases, as well as expand the understanding of changes in the morphological picture of a woman's ovaries with age.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>яичник</kwd><kwd>старение</kwd><kwd>морфометрия</kwd><kwd>мозговое и корковое вещество</kwd><kwd>белочная оболочка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ovary</kwd><kwd>aging</kwd><kwd>morphometry</kwd><kwd>cerebral and cortical matter</kwd><kwd>protein membrane</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rowe J.W., Kahn R.L. Human aging: usual and successful. Science. 1987;237(4811):143-9. https://doi.org/10.1126/science.3299702</mixed-citation><mixed-citation xml:lang="en">Rowe J.W., Kahn R.L. Human aging: usual and successful. 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