<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2024.4.MORPH.4</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-1110</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Морфология, патология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Morphology, pathology</subject></subj-group></article-categories><title-group><article-title>Абсцесс Броди плечевой кости – причина развития сепсиса у пациента с коронавирусной инфекцией (COVID-19)</article-title><trans-title-group xml:lang="en"><trans-title>Brody's abscess of the humerus is the cause of sepsis in a patient with coronavirus infection (COVID-19)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9303-7640</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кислов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kislov</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кислов Максим Александрович, д-р мед. наук, доцент, заведующий кафедрой морфологии Института анатомии и морфологии</p><p>ул. Островитянова д. 1, г. Москва, 11799</p></bio><bio xml:lang="en"><p>Maksim A. Kislov, Dr. Sci. (Med.), Docent, Head of the Department of Morphology at the Institute of Anatomy and Morphology</p><p>1 Ostrovityanova str., Moscow, 117997</p></bio><email xlink:type="simple">smedik@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1936-4448</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Максимов Александр Викторович, д-р мед. наук, доцент, заведующий кафедрой фундаментальных медицинских дисциплин</p><p>ул. Радио, д. 10А, стр. 2, г. Москва, 105005</p></bio><bio xml:lang="en"><p>Aleksandr V. Maksimov, Dr. Sci. (Med.), Docent, Head of the Department of Fundamental Medical Disciplines</p><p>10A Radio str., building 2, Moscow, 105005</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1350-0704</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Супильников</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Supilnikov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Супильников Алексей Александрович, канд. мед. наук, доцент, первый проректор по научной деятель- ности</p><p>ул. Чапаевская, д. 227, г. Самара, 443001</p></bio><bio xml:lang="en"><p>Aleksey A. Supilnikov, Cand. Sci. (Med.), Docent, vice-rector for scientific work</p><p>227 Chapaevskaya str., Samara, 443001</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.I. Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственный университет просвещения</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State University of Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Медицинский университет «Реавиз»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical University "Reaviz"</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>18</day><month>10</month><year>2024</year></pub-date><volume>14</volume><issue>4</issue><fpage>24</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кислов М.А., Максимов А.В., Супильников А.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Кислов М.А., Максимов А.В., Супильников А.А.</copyright-holder><copyright-holder xml:lang="en">Kislov M.A., Maksimov A.V., Supilnikov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/1110">https://vestnik.reaviz.ru/jour/article/view/1110</self-uri><abstract><sec><title>Цель</title><p>Цель: провести клинико-морфологический анализ случая наступления смерти в результате сепсиса, причиной которого являлся абсцесс Броди.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Был проведён анализ летального исхода пациента 54 лет, наступившего в стационаре медицинской организации, где ему оказывалась лечебная помощь по поводу заболевания – новой коронавирусной инфекции. Проводимый комплекс клинико-лабораторных и инструментальных методов диагностики не мог объяснить прогрессивное ухудшение тяжести состояния пациента и наступление летального исхода.</p></sec><sec><title>Результаты</title><p>Результаты. При проведении аутопсии был установлен абсцесс проксимального эпифиза левой плечевой кости с распространением воспалительного процесса на мягкие ткани груди, пристеночную плевру с развитием гнойно-фибринозного плеврита, левосторонней пневмонии, гнойно-фибринозного перикардита, гематогенного гнойного менингита.</p></sec><sec><title>Заключение</title><p>Заключение. Авторами статьи установлена казуистичная причина смерти от абсцесса Броди, что позволяет расширить диагностический поиск в случае сепсиса с неясным первичным очагом.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: To conduct a clinical and morphological analysis of the case of death as a result of sepsis, the cause of which was Brody's abscess.</p></sec><sec><title>Material and methods</title><p>Material and methods. An analysis of the fatal outcome of a 54–year-old patient who occurred in a hospital of a medical organization where he received medical care for a disease – a new coronavirus infection. The complex of clinical, laboratory and instrumental diagnostic methods could not explain the progressive deterioration of the severity of the patient's condition and the onset of death.</p></sec><sec><title>Results</title><p>Results. During the autopsy, an abscess of the proximal epiphysis of the left humerus was found with the spread of the inflammatory process to the soft tissues of the breast, the parietal pleura with the development of purulent fibrinous pleurisy, left-sided pneumonia, purulent fibrinous pericarditis, hematogenous purulent meningitis.</p></sec><sec><title>Conclusion</title><p>Conclusion. The authors of the article have established a causal cause of death from Brody's abscess, which makes it possible to expand the diagnostic search in the case of sepsis with an unclear primary focus.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>остеомиелит</kwd><kwd>абсцесс Броди</kwd><kwd>сепсис</kwd><kwd>коронавирусная инфекция (COVID-19)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>osteomyelitis</kwd><kwd>Brody's abscess</kwd><kwd>sepsis</kwd><kwd>coronavirus infection (COVID-19)</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ковалинин В.В., Клещевникова К.Ю., Джанчатова Б.А. Лучевая диагностика остеомиелита. Российский электронный журнал лучевой диагностики. 2014; 4 (3): 66-77.</mixed-citation><mixed-citation xml:lang="en">Kovalinin V.V., Kleshchevnikova K.Yu., Dzhanchatova B.A. Radiation diagnosis of osteomyelitis. The Russian electronic Journal of Radiation Diagnostics. 2014;4(3):66-77. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Григоровский В.В. Аспекты патоморфологии и номенклатуры в современной классификации неспецифических остеомиелитов. Ортопедия, травматология и протезирование. 2013;3 (592):77–87.</mixed-citation><mixed-citation xml:lang="en">Grigorovsky V.V. Aspects of pathomorphology and nomenclature in the modern classification of nonspecific osteomyelitis. Orthopedics, traumatology and prosthetics. 2013;3(592):77–87. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Hammad A., Leute P.J. F., Hoffmann I., Hoppe S., Lakemeier S., Klinger, H. M. et al. Acute leg pain with suspected beginning leg compartment syndrome and deep vein thrombosis as differential diagnoses in an unusual presentation of Brodie’s abscess: a case report. Journal of Medical Case Reports. 2015;9:292.</mixed-citation><mixed-citation xml:lang="en">Hammad A., Leute P.J. F., Hoffmann I., Hoppe S., Lakemeier S., Klinger, H. M. et al. Acute leg pain with suspected beginning leg compartment syndrome and deep vein thrombosis as differential diagnoses in an unusual presentation of Brodie’s abscess: a case report. Journal of Medical Case Reports. 2015;9:292.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kanoun M. L., Khorbi A., Khmiri C., Tebourbi A., Hadded N. et al. Diagnostic et traitement de l'abces de brodie chez l'adulte: a propos de vingt patients. Tunisie médicale. 2017;85(10):857-861.</mixed-citation><mixed-citation xml:lang="en">Kanoun M. L., Khorbi A., Khmiri C., Tebourbi A., Hadded N. et al. Diagnostic et traitement de l'abces de brodie chez l'adulte: a propos de vingt patients. Tunisie médicale. 2017;85(10):857-861.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">De Smet L., Fabry G. Primary subacute osteomyelitis of the wrist in children. Acta orthopaedica belgica. 1995:282-285.</mixed-citation><mixed-citation xml:lang="en">De Smet L., Fabry G. Primary subacute osteomyelitis of the wrist in children. Acta orthopaedica belgica. 1995:282-285.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Овденко А.Г. Современные методы лечения гнойных осложнений в травматологии и ортопедии. Церковь и медицина. 2017;1:65-73.</mixed-citation><mixed-citation xml:lang="en">Ovdenko A.G. Modern methods of treatment of purulent complications in traumatology and orthopedics. The Church and medicine. 2017; 1:65-73. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Pretorius E.S., Fishman E.K. Volumerendered three dimensional spiral CT: musculoskeletal applications. Radiographics. 1999;19(5):1143–1160.</mixed-citation><mixed-citation xml:lang="en">Pretorius E.S., Fishman E.K. Volumerendered three dimensional spiral CT: musculoskeletal applications. Radiographics. 1999;19(5):1143–1160.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Chen BC, Kobayashi T, O’Rourke H, Sekar P. Staphylococcus aureus osteomyelitis causing Brodie’s abscess of the tibia in an adult man. BMJ Case Reports CP. 2021;14(1):240836.</mixed-citation><mixed-citation xml:lang="en">Chen BC, Kobayashi T, O’Rourke H, Sekar P. Staphylococcus aureus osteomyelitis causing Brodie’s abscess of the tibia in an adult man. BMJ Case Reports CP. 2021;14(1):240836.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Patel M. K., Barrientos S., Gupta S. et al. Subacute knee pain and swelling in a healthy male: a case of Brodie’s abscess. BMJ Case Reports CP. 2019;12 (3):227926.</mixed-citation><mixed-citation xml:lang="en">Patel M. K., Barrientos S., Gupta S. et al. Subacute knee pain and swelling in a healthy male: a case of Brodie’s abscess. BMJ Case Reports CP. 2019;12 (3):227926.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
