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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2025.6.CLIN.1</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-1349</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Особенности полиморбидной патологии у пациентов пожилого и старческого возраста с хронической болезнью почек</article-title><trans-title-group xml:lang="en"><trans-title>Characteristic features of polymorbid pathology in elder and senile patients with chronic kidney disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6597-3872</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рогозина</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rogozina</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рогозина Лариса Александровна. Канд. мед. наук, доцент кафедры госпитальной терапии с курсами гематологии и трансфузиологии</p><p>ул. Чапаевская, д. 89, г. Самара, 443099</p></bio><bio xml:lang="en"><p>Larisa A. Rogozina. Cand. Sci. (Med.), Associate Professor Department of Hospital Therapy with Courses in Hematology and Transfusiology</p><p>Chapaevskaya St., 89, Samara, 443099</p></bio><email xlink:type="simple">larissarogozina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9351-6177</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рубаненко</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rubanenko</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рубаненко Олеся Анатольевна. Д-р мед. наук, профессор кафедры госпитальной терапии с курсами гематологии и трансфузиологии</p><p>ул. Чапаевская, д. 89, г. Самара, 443099</p></bio><bio xml:lang="en"><p>Olesya A. Rubanenko. Dr. Sci. (Med.), Professor of the Department of Hospital Therapy withCourses in Hematology and Transfusiology</p><p>Chapaevskaya St., 89, Samara, 443099</p></bio><email xlink:type="simple">olesya.rubanenko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3996-4689</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рубаненко</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Rubanenko</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рубаненко Анатолий Олегович. Канд. мед. наук, доцент кафедры пропедевтической терапии с курсом кардиологии</p><p>ул. Чапаевская, д. 89, г. Самара, 443099</p></bio><bio xml:lang="en"><p>Anatoliy O. Rubanenko. Cand. Sci. (Med.), Associate Professor of the Department of Propedeutic Therapy with a Course in Cardiology</p><p>Chapaevskaya St., 89, Samara, 443099</p></bio><email xlink:type="simple">a.o.rubanenko@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0645-7645</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давыдкин</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Davydkin</surname><given-names>I. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Давыдкин Игорь Леонидович. Д-р мед. наук, профессор, заведующий кафедрой госпитальной терапии с курсами гематологии и трансфузиологиии</p><p>ул. Чапаевская, д. 89, г. Самара, 443099</p></bio><bio xml:lang="en"><p>Igor' L. Davydkin. Dr. Sci. (Med.), Professor, Head of the Department of Hospital Therapy with Courses in Hematology and Transfusiology</p><p>Chapaevskaya St., 89, Samara, 443099</p></bio><email xlink:type="simple">i.l.davydkin@samsmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Самарский государственный медицинский университет<country>Россия</country></aff><aff xml:lang="en">Samara State Medical University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>10</day><month>03</month><year>2026</year></pub-date><volume>15</volume><issue>6</issue><fpage>12</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рогозина Л.А., Рубаненко О.А., Рубаненко А.О., Давыдкин И.Л., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Рогозина Л.А., Рубаненко О.А., Рубаненко А.О., Давыдкин И.Л.</copyright-holder><copyright-holder xml:lang="en">Rogozina L.A., Rubanenko O.A., Rubanenko A.O., Davydkin I.L.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/1349">https://vestnik.reaviz.ru/jour/article/view/1349</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: изучить распространённость и особенности полиморбидной патологии у пациентов пожилого и старческого возраста с хронической болезнью почек в амбулаторной практике. </p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведено одномоментное кросссекционное исследование 787 пациентов с ХБП: 630 человек пожилого возраста (медиана 67 лет) и 157 человек старческого возраста (медиана 77 лет). Оценивались ИМТ, СКФ по формуле CKD-EPI, протеинурия, сопутствующая патология, липидный профиль, осведомленность о ХБП.</p></sec><sec><title>Результаты</title><p>Результаты. Ожирение выявлено у 53,2% пациентов пожилого и 46,1% старческого возраста. Артериальная гипертензия диагностирована у 84,3% и 93,6%, сахарный диабет – у 85,6% и 92,4% соответственно. Наиболее часто встречались С2 (51,3% и 46,2%) и С3 (23,5% и 40,2%) стадии ХБП. Осведомленность о наличии ХБП составила лишь 10,6% в первой группе и 21,0% во второй. Консультацию нефролога получили только 26% и 22,9% пациентов соответственно.</p></sec><sec><title>Заключение</title><p>Заключение. У пациентов пожилого и старческого возраста с ХБП отмечается высокая распространённость факторов кардиоваскулоренометаболического риска при критически низкой осведомленности о почечной патологии и недостаточном нефрологическом контроле. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to study the prevalence and characteristics of polymorbid pathology in elderly and senile patients with chronic kidney disease in outpatient practice.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A cross-sectional study of 787 CKD patients was conducted: 630 elderly patients (median age 67 years) and 157 senile patients (median age 77 years). BMI, GFR by CKD-EPI formula, proteinuria, comorbidities, lipid profile, and CKD awareness were assessed.</p></sec><sec><title>Results</title><p>Results. Obesity was detected in 53.2% of elderly and 46.1% of senile patients. Arterial hypertension was diagnosed in 84.3% and 93.6%, diabetes mellitus in 85.6% and 92.4%, respectively. CKD stages C2 (51.3% and 46.2%) and C3 (23.5% and 40.2%) were most common. CKD awareness was only 10.6% in the first group and 21.0% in the second. Only 26% and 22.9% of patients received nephrological consultation, respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. Elderly and senile patients with CKD demonstrate high prevalence of cardiovasculorenal metabolic risk factors with critically low awareness of kidney disease and insufficient nephrological control. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая болезнь почек [D051436]</kwd><kwd>пожилой возраст [D000368]</kwd><kwd>старческий возраст [D000369]</kwd><kwd>полиморбидность [D000071069]</kwd><kwd>кардиоренальный синдром [D000072096]</kwd><kwd>метаболический синдром [D024821]</kwd><kwd>ожирение [D009765]</kwd><kwd>артериальная гипертензия [D006973]</kwd><kwd>сахарный диабет 2 типа [D003924]</kwd><kwd>скорость клубочковой фильтрации [D005919]</kwd><kwd>протеинурия [D011507]</kwd><kwd>коморбидность [D015897]</kwd><kwd>сердечно-сосудистые заболевания [D002318]</kwd><kwd>амбулаторная помощь [D000553]</kwd><kwd>факторы риска [D012307]</kwd><kwd>хроническая сердечная недостаточность [D006333]</kwd><kwd>гериатрия [D005853]</kwd></kwd-group><kwd-group xml:lang="en"><kwd>renal insufficiency</kwd><kwd>chronic [D051436]</kwd><kwd>aged [D000368]</kwd><kwd>aged</kwd><kwd>80 and over [D000369]</kwd><kwd>multimorbidity [D000071069]</kwd><kwd>cardiorenal syndrome [D000072096]</kwd><kwd>metabolic syndrome [D024821]</kwd><kwd>obesity [D009765]</kwd><kwd>hypertension [D006973]</kwd><kwd>diabetes mellitus</kwd><kwd>type 2 [D003924]</kwd><kwd>glomerular filtration rate [D005919]</kwd><kwd>proteinuria [D011507]</kwd><kwd>comorbidity [D015897]</kwd><kwd>cardiovascular diseases [D002318]</kwd><kwd>ambulatory care [D000553]</kwd><kwd>risk factors [D012307]</kwd><kwd>heart failure [D006333]</kwd><kwd>geriatrics [D005853]</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Anavekar NS, McMurray JJ, Velazquez EJ, Solomon SD, Kober L, Rouleau JL, White HD, Nordlander R, Maggioni A, Dickstein K, Zelenkofske S, Leimberger JD, Califf RM, Pfeffer MA. 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