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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2021.1.TX.2</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-153</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Донорство и трансплантация органов и тканей</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Organ and tissue donation and transplantation</subject></subj-group></article-categories><title-group><article-title>Эхография при трансплантации печени: обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>Echography in liver transplantation: a literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1230-1076</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Донова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Donova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Донова Любовь Викторовна, кандидат медицинских наук, старший научный сотрудник отделения трансплантации печени</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6362-7914</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новрузбеков</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Novruzbekov</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Новрузбеков Мурад Сафтарович, доктор медицинских наук, заведующий научным отделением трансплантации печени</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5057-6628</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Магомедов</surname><given-names>К. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Magomedov</surname><given-names>K. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Магомедов Кубай Магомедович, врач-хирург центра трансплантации печени</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ СП им. Н.В. Склифосовского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Emergency Medicine named after N.V. Sklifosovsky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>87</fpage><lpage>96</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Донова Л.В., Новрузбеков М.С., Магомедов К.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Донова Л.В., Новрузбеков М.С., Магомедов К.М.</copyright-holder><copyright-holder xml:lang="en">Donova L.V., Novruzbekov M.S., Magomedov K.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/153">https://vestnik.reaviz.ru/jour/article/view/153</self-uri><abstract><p>Трансплантация печени справедливо считается единственным радикальным методом лечения терминальных хронических заболеваний печени и пациентов с острой печеночной недостаточностью. Однако, несмотря на накопленный опыт ведения пациентов этой группы, уровень развития осложнений остается еще на достаточно высоком уровне. Успех коррекции возникающих патологических состояний в значительной степени зависит от сроков их диагностики. Поскольку развивающиеся после трансплантации печени осложнения чаще всего не имеют специфических клинико-биохимических проявлений, использование визуализационных методов исследования играет ключевую роль в оценке состояния трансплантированного органа на всех этапах послеоперационного периода. Среди всех инструментальных методов ультразвуковое исследование с использованием допплеровских методик, проводимое в почасовом режиме непосредственно в палате интенсивной терапии, с точностью до 97 % и специфичностью до 100 % позволяет выявлять сосудистые посттрансплантационные осложнения в максимально короткие сроки. Их своевременная коррекция позволяет избежать потери трансплантата. Использование динамического наблюдения способствует дифференциальной диагностике в выявлении несосудистых осложнений на разных этапах послеоперационного периода. Применение современных методик в значительной степени расширяют возможности эхографии. Так, применение контрастного усиления не только сокращает время исследования, но и повышает чувствительность доплерографии в оценке проходимости сосудистого русла, особенно у пациентов со снижением центральной гемодинамики. Использование методик ARFI-эластографии у пациентов в поздние сроки послеоперационного периода дает возможность объективно оценивать степень выраженности фиброза печеночного трансплантата.</p></abstract><trans-abstract xml:lang="en"><p>Liver transplantation is rightly considered the only radical treatment for terminal chronic liver diseases and patients with acute liver failure. However, despite the accumulated experience in the management of patients in this group, the level of complications development remains at a fairly high level. The success of the correction of emerging pathological conditions largely depends on the timing of their diagnosis. Since complications developing after liver transplantation most often do not have specific clinical and biochemical manifestations, the use of imaging research methods plays a key role in assessing the state of the transplanted organ at all stages of the postoperative period. Among all instrumental methods, ultrasound examination using Doppler techniques, carried out hourly directly in the intensive care unit, with an accuracy of 97 % and a specificity of up to 100 %, makes it possible to detect vascular post-transplant complications as soon as possible. Their timely correction avoids the loss of the graft. The use of dynamic observation contributes to differential diagnosis in identifying non-vascular complications at different stages of the postoperative period. The use of modern techniques greatly expands the possibilities of echography. Thus, the use of contrast enhancement not only shortens the study time, but also increases the sensitivity of Dopplerography in assessing the patency of the vascular bed, especially in patients with decreased central hemodynamics. The use of ARFI-elastography techniques in patients in the late postoperative period makes it possible to objectively assess the severity of hepatic graft fibrosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трансплантация печени</kwd><kwd>эхолокация</kwd><kwd>отторжение трансплантата</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver transplantation</kwd><kwd>echolocation</kwd><kwd>graft rejection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Crossin JD, Muradali D, Wilson SR. US of liver transplants: normal and abnormal. RadioGraphics. 2003;23(5):1093–1114. PMID: 12975502 https://doi.org/ =10.1148/rg.235035031</mixed-citation><mixed-citation xml:lang="en">1 Crossin JD, Muradali D, Wilson SR. US of liver transplants: normal and abnormal. RadioGraphics. 2003;23(5):1093–1114. 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