vmireavizВестник медицинского института «РЕАВИЗ». Реабилитация, Врач и ЗдоровьеBulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)2226-762X2782-1579РЕАВИЗvmireaviz-20Research ArticleКлиническая медицинаClinical medicineВысокоинтенсивная фокусированная ультразвуковая абляция (HIFU) в лечении рака предстательной железы (обзор литературы)High-intensity focused ultrasound (HIFU) in the treatment of prostate cancer (literature review)СолововВ. А.SolovovV. A.

Соловов Вячеслав Александрович, доктор медицинских наук, заведующий отделением интервенционных методов диагностики и лечения

Самара

ТюринА. А.TyurinA. A.

Тюрин Александр Александрович, врач-онколог

Самара

ГБУЗ «Самарский областной клинический онкологический диспансер»РоссияState Budgetary Healthcare Institution ‘Samara Regional Clinical Oncology dispensary’Russian FederationМедицинский госпиталь ИДКРоссияMedical Hospital IDKRussian Federation202024112020016670Copyright © Соловов В.А., Тюрин А.А., 20202020Соловов В.А., Тюрин А.А.Solovov V.A., Tyurin A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestnik.reaviz.ru/jour/article/view/20

В настоящее время рак предстательной железы остается одной из самых распространенных злокачественных опухолей в структуре онкоурологической патологии. В данной статье представлен обзор литературы, описывающий опыт использования современного неинвазивного способа лечения РПЖ – высокоинтенсивной сфокусированной ультразвуковой абляции (high intensive focused ultrasound – HIFU), проанализированы данные последних исследований, связанных с данной технологией лечения РПЖ.

Prostate cancer remains one of the most common urological malignancies. This article aims to describe the experience of using high-intensity focused ultrasound (HIFU), a non-invasive method for the treatment of prostate cancer, and to summarize the results of latest studies on this problem.

рак предстательной железывысокоинтенсивная сфокусированная ультразвуковая абляция (HIFU)prostate cancerhigh-intensity focused ultrasound (HIFU)ReferencesAlekseev B.Ya., Kaprin A.D., Matveev V.B., Nyushko K.M. Klinicheskie rekomendacii po diagnostike i leche-niyu raka predstatel'noj zhelezy. – M., 2014.Alekseev B.Ya., Kaprin A.D., Matveev V.B., Nyushko K.M. Klinicheskie rekomendacii po diagnostike i leche-niyu raka predstatel'noj zhelezy. – M., 2014.Alyaev Yu.G., Glybochko P.V., Pushkar' D.Yu., redaktory. Urologiya. Rossijskie klinicheskie rekomendacii. – M.: GEOTAR-Media, 2016. – 496 s.Alyaev Yu.G., Glybochko P.V., Pushkar' D.Yu., redaktory. Urologiya. Rossijskie klinicheskie rekomendacii. – M.: GEOTAR-Media, 2016. – 496 s.Kaprin A.D., Kostin A.A., Starinskij V.V., Samsonov Yu.V., Grecova O.P. Rak predstatel'noj zhelezy: organizacionnye problemy rannego vyyavleniya pri dispanserizacii muzhskogo naseleniya Rossii. Research'nPracticalMedicineJournal. – 2016. – Specvypusk.Kaprin A.D., Kostin A.A., Starinskij V.V., Samsonov Yu.V., Grecova O.P. Rak predstatel'noj zhelezy: organizacionnye problemy rannego vyyavleniya pri dispanserizacii muzhskogo naseleniya Rossii. Research'nPracticalMedicineJournal. – 2016. – Specvypusk.Klinicheskie rekomendacii po diagnostike i lecheniyu raka predstatel'noj zhelezy. – M., 2018.Klinicheskie rekomendacii po diagnostike i lecheniyu raka predstatel'noj zhelezy. – M., 2018.Glybochko P.V., Alyaev Yu.G., Amosov A.V. i soavtory. Gistoskanning v rannej diagnostike raka predstatel'noj zhelezy // Medicinskij Vestnik Bashkortostana. – 2013. – T. 8. – № 2.Glybochko P.V., Alyaev Yu.G., Amosov A.V. i soavtory. Gistoskanning v rannej diagnostike raka predstatel'noj zhelezy // Medicinskij Vestnik Bashkortostana. – 2013. – T. 8. – № 2.Sulejmanov E. A., Filonenko E. V., Moskvicheva L. I. i soavtory. Vozmozhnosti HIFU-terapii na sovremen-nom etape. Research'nPractical Medicine Journal. – 2016. – T. 3. – № 3.Sulejmanov E. A., Filonenko E. V., Moskvicheva L. I. i soavtory. Vozmozhnosti HIFU-terapii na sovremen-nom etape. Research'nPractical Medicine Journal. – 2016. – T. 3. – № 3.Wood R. W., Loomis A. The physical and biological effects of high frequency soundwaves of great intensity. Phil. Mag. – 1927. – № 4. – S. 417.Wood R. W., Loomis A. The physical and biological effects of high frequency soundwaves of great intensity. Phil. Mag. – 1927. – № 4. – S. 417.Burov A.K. High-intensity ultrasonic vibrations for action on animal and human malignant tumours. Dokl. Akad. Nauk USSR. – 1956. – № 106. – S. 239–41.Burov A.K. High-intensity ultrasonic vibrations for action on animal and human malignant tumours. Dokl. Akad. Nauk USSR. – 1956. – № 106. – S. 239–41.Rozenberg L. D., redaktor. Fokusiruyushchie izluchateli ul'trazvuka. Fizika i tekhnika moshchnogo ul'trazvuka // Istochnikimoshchnogoul'trazvuka. – M.: Nauka. – 1967. – S. 149–206.Rozenberg L. D., redaktor. Fokusiruyushchie izluchateli ul'trazvuka. Fizika i tekhnika moshchnogo ul'trazvuka // Istochnikimoshchnogoul'trazvuka. – M.: Nauka. – 1967. – S. 149–206.Maderbacher, S., Pedevilla, M., Vinger, L., Susani, M. and Marberger, M. (1955) Effect of High-Intensity Focused Ultrasound on Human Prostate Cancer in Vivo. Cancer Research, 55, 3346-3351.Maderbacher, S., Pedevilla, M., Vinger, L., Susani, M. and Marberger, M. (1955) Effect of High-Intensity Focused Ultrasound on Human Prostate Cancer in Vivo. Cancer Research, 55, 3346-3351.Gelet A., Chapelon JY., Poissonnier L. et al. Local recurrence of prostate cancer after external beam radiotherapy: early experience of salvage therapy using high intensity focused ultrasonography. Urology. 2004;63:625–29.Gelet A., Chapelon JY., Poissonnier L. et al. Local recurrence of prostate cancer after external beam radiotherapy: early experience of salvage therapy using high intensity focused ultrasonography. Urology. 2004;63:625–29.Uchida, T., Shoji, S., Nakano, M., Hongo, S., Nitta, M., Murota, A. and Nagata, Y. (2009) Transrectal HighIntensity Focused Ultrasound for the Treatment of Localized Prostate Cancer; Eight-Year Experience. International Journal of Urology, 16, 881-886.Uchida, T., Shoji, S., Nakano, M., Hongo, S., Nitta, M., Murota, A. and Nagata, Y. (2009) Transrectal HighIntensity Focused Ultrasound for the Treatment of Localized Prostate Cancer; Eight-Year Experience. International Journal of Urology, 16, 881-886.Barnett SB., terHaar GR, Ziskin MC, et al. Current status of research on biophysical effects of ultrasound. UltrasoundMedBiol. 1994;20:205–18.Barnett SB., terHaar GR, Ziskin MC, et al. Current status of research on biophysical effects of ultrasound. UltrasoundMedBiol. 1994;20:205–18.Karpov O.E., Vetshev P.S., Zhivotov V.A. Ul'trazvukovaya ablyaciya opuholej – sostoyanie i perspektivy // Vestnik Nacional'nogo mediko-hirurgicheskogo Centra im. N.I. Pirogova. – 2008. – № 3 (2). – S. 77–82.Karpov O.E., Vetshev P.S., Zhivotov V.A. Ul'trazvukovaya ablyaciya opuholej – sostoyanie i perspektivy // Vestnik Nacional'nogo mediko-hirurgicheskogo Centra im. N.I. Pirogova. – 2008. – № 3 (2). – S. 77–82.Hynynen K., Pomeroy O., Smith D. N. et al. MR imaging-guided focused ultrasound surgery of fibroadenomas in the breast: A feasibility. Radiology. – 2001. – № 219. – С. 176–185.Hynynen K., Pomeroy O., Smith D. N. et al. MR imaging-guided focused ultrasound surgery of fibroadenomas in the breast: A feasibility. Radiology. – 2001. – № 219. – С. 176–185.Wu F., Wang Z. B., Wang Z. L., et al. Changes in ultrasonic image of tissue damaged by high intensity ultrasound in vivo. J. Acoustic Soc. Am. – 1998. – 103. – С. 2869.Wu F., Wang Z. B., Wang Z. L., et al. Changes in ultrasonic image of tissue damaged by high intensity ultrasound in vivo. J. Acoustic Soc. Am. – 1998. – 103. – С. 2869.Rebillard X., Soulié M., Chartier-Kastler E., Davin JL., Mignard JP., Moreau JL. et al. High-intensity focused ultrasound in prostate cancer; a systematic literature review of the French Association of Urology. BJU Int 2008; 101: 1205-13.Rebillard X., Soulié M., Chartier-Kastler E., Davin JL., Mignard JP., Moreau JL. et al. High-intensity focused ultrasound in prostate cancer; a systematic literature review of the French Association of Urology. BJU Int 2008; 101: 1205-13.Chaussy CG. Ultrasonidos de altaintensidadfocalizados (HIFU) para el tratamiento local del cancer de prostata: papel actual. Archivos Españoles de Urología. 2011;64:493–96.Chaussy CG. Ultrasonidos de altaintensidadfocalizados (HIFU) para el tratamiento local del cancer de prostata: papel actual. Archivos Españoles de Urología. 2011;64:493–96.Chiang P. H., Liu Y. Y. Comparisons of oncological and functional outcomes among radical retropubic prostatectomy, high dose rate brachytherapy, cryoablation and high-intensity focused ultrasound for localized prostate cancer // Springerplus. – 2016. – № 5 (1). – С. 1905.Chiang P. H., Liu Y. Y. Comparisons of oncological and functional outcomes among radical retropubic prostatectomy, high dose rate brachytherapy, cryoablation and high-intensity focused ultrasound for localized prostate cancer // Springerplus. – 2016. – № 5 (1). – С. 1905.Guillaumier S., Peters M., Arya M., et al. A Multicentre Study of 5-year outcomes following focal therapy in treating clinically significant nonmetastatic prostate cancer. European Urology, Vol. 74, Issue 4, October 2018, Pages 422-429.Guillaumier S., Peters M., Arya M., et al. A Multicentre Study of 5-year outcomes following focal therapy in treating clinically significant nonmetastatic prostate cancer. European Urology, Vol. 74, Issue 4, October 2018, Pages 422-429.Dickinson L., Arya M., EmbertonM. Medium-term Outcomes after Whole-gland High-intensity Focused Ultrasound for the Treatment of Non metastatic Prostate Cancer from a Multicentre Registry Cohort. Eur. Urol. – 2016. – S0302-2838(16) 00244-X.Dickinson L., Arya M., EmbertonM. Medium-term Outcomes after Whole-gland High-intensity Focused Ultrasound for the Treatment of Non metastatic Prostate Cancer from a Multicentre Registry Cohort. Eur. Urol. – 2016. – S0302-2838(16) 00244-X.Hayashi1 M., Hayashi T., Oka T., Goto K., Shinmei S., Inoue Y., Inoue K. Long-term outcomes and prognosis of transrectal high-intensity focused ultrasound therapy for patients with localized prostate cancer – therapy after recurrence and predictive factors. Open Journal of Urology Vol. 07 No. 06(2017), Article ID:77326,16 pagesHayashi1 M., Hayashi T., Oka T., Goto K., Shinmei S., Inoue Y., Inoue K. Long-term outcomes and prognosis of transrectal high-intensity focused ultrasound therapy for patients with localized prostate cancer – therapy after recurrence and predictive factors. Open Journal of Urology Vol. 07 No. 06(2017), Article ID:77326,16 pagesGanzer R., Fritsche H. M., Brandtner A.et al. Fourteen-year oncological and functional outcomes of highintensity focused ultrasound in localized prostate cancer. BJU Int. – 2013. – 112(3). – С. 322-9.Ganzer R., Fritsche H. M., Brandtner A.et al. Fourteen-year oncological and functional outcomes of highintensity focused ultrasound in localized prostate cancer. BJU Int. – 2013. – 112(3). – С. 322-9.Solovov V. A., Orlov A. E., Vozdvizhenskij M. O. Vysokointensivnaya fokusirovannaya ul'trazvukovaya ablyaciya raka predstatel'noj zhelezy u 976 pacientov: 7-letnie rezul'taty // Izvestiya. – 2015. – T. 17. – №. 2-3. – S. 682–685.Solovov V. A., Orlov A. E., Vozdvizhenskij M. O. Vysokointensivnaya fokusirovannaya ul'trazvukovaya ablyaciya raka predstatel'noj zhelezy u 976 pacientov: 7-letnie rezul'taty // Izvestiya. – 2015. – T. 17. – №. 2-3. – S. 682–685.Popkov V. M., Fomkin R. N., Blyumberg B. I. Vozmozhnosti prognozirovaniya recidiva raka prostaty posle HIFU-ablacii s pomoshch'yu matematicheskogo modelirovaniya // Saratovskij nauchno-medicinskij zhurnal. – 2013. – T. 9. – №. 2.Popkov V. M., Fomkin R. N., Blyumberg B. I. Vozmozhnosti prognozirovaniya recidiva raka prostaty posle HIFU-ablacii s pomoshch'yu matematicheskogo modelirovaniya // Saratovskij nauchno-medicinskij zhurnal. – 2013. – T. 9. – №. 2.Limani, K., Aoun, F., Holz, S., Paesmans, M., Peltier, A., Van Velthoven, R. Single high intensity focused ultrasound session as a whole gland primary treatment for clinically localized prostate cancer: 10-year outcomes. Prostate cancer, 2014.Limani, K., Aoun, F., Holz, S., Paesmans, M., Peltier, A., Van Velthoven, R. Single high intensity focused ultrasound session as a whole gland primary treatment for clinically localized prostate cancer: 10-year outcomes. Prostate cancer, 2014.British Uro-oncology Group, British Association of Urological Surgeons, Section of Oncology, British Prostate Group. MDT (multidisciplinary team) guidance for managing prostate cancer. Second edition. British Association of Urological Surgeons. Website http://www.baus.org.uk/AboutBAUS/publications/mdt-prostate.British Uro-oncology Group, British Association of Urological Surgeons, Section of Oncology, British Prostate Group. MDT (multidisciplinary team) guidance for managing prostate cancer. Second edition. British Association of Urological Surgeons. Website http://www.baus.org.uk/AboutBAUS/publications/mdt-prostate.

The authors declare that there are no conflicts of interest present.