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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2021.3.DENT.1</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-229</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Вопросы стоматологии</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Dentistry</subject></subj-group></article-categories><title-group><article-title>ОСОБЕННОСТИ ТРОФИКИ КОСТНОЙ ТКАНИ ПОСЛЕ УСТАНОВКИ ДЕНТАЛЬНЫХ ИМПЛАНТАТОВ</article-title><trans-title-group xml:lang="en"><trans-title>FEATURES OF TROPHISM OF BONE TISSUE AFTER THE INSTALLATION OF DENTAL IMPLANTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1825-0097</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иващенко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivaschenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> доктор медицинских наук, доцент кафедры ортопедической стоматологии</p><p> Самара </p></bio><bio xml:lang="en"><p>Samara</p></bio><email xlink:type="simple">s1131149@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8281-3472</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яблоков</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Yablokov</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кандидат медицинских наук, врач-стоматолог-хирург стоматологического отделения</p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><email xlink:type="simple">s1131149@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9448-8232</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Марков</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Markov</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p> доктор медицинских наук, профессор кафедры клинической медицины последипломного образования</p><p>Самара </p></bio><bio xml:lang="en"><p>Samara</p></bio><email xlink:type="simple">ivachencoaveg@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5522-0420</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Монаков</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Monakov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кандидат медицинских наук, ассистент кафедры челюстно-лицевой хирургии и стоматологии</p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><email xlink:type="simple">ivachencoaveg@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7970-4913</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нестеров</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Nesterov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p> доктор медицинских наук, профессор кафедры ортопедической стоматологии</p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><email xlink:type="simple">ivachencoaveg@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО СамГМУ Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Медицинский университет Реавиз</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical University “Reaviz”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО СамГМУ Миздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>06</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>3</issue><fpage>79</fpage><lpage>84</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иващенко А.В., Яблоков А.Е., Марков И.И., Монаков В.А., Нестеров А.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Иващенко А.В., Яблоков А.Е., Марков И.И., Монаков В.А., Нестеров А.М.</copyright-holder><copyright-holder xml:lang="en">Ivaschenko A.V., Yablokov A.E., Markov I.I., Monakov V.A., Nesterov A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/229">https://vestnik.reaviz.ru/jour/article/view/229</self-uri><abstract><sec><title> Актуальность</title><p> Актуальность. Важнейшим условием успешного результата дентальной имплантации является качественная остеоинтеграция дентальных имплантатов. В литературе широко освещается вопрос качества  остеоинтеграции, которое непосредственно зависит от первичной  стабильности дентальных имплантатов. В зоне ремоделирования  костной ткани, окружающей установленные дентальные имплантаты,  происходят перманентные процессы резорбции костной ткани и ее  восстановления [1, 2]. </p><p>Цель – выявить реакционную способность щелочной фосфатазы и остеокальцина в биологической жидкости (слюне) у пациентов после установки дентальных имплантатов. </p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Сбор и анализ клинического материала осуществлялся на базе Клиник ФГБОУ ВО «Самарский государственный  медицинский университет» Минздрава России. Была проведена  операция дентальной имплантации у 184 пациентов в возрасте от 32 до  65 лет. Соотношение по гендерному признаку составляло 2:3 (40  мужчин и 60 женщин). Зубы были утрачены вследствие неудовлетворительной гигиены полости рта, осложнений кариеса. </p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. На момент поступления пациентов в  отделение кафедры ортопедической стоматологии Клиник СамГМУ  основная масса пациентов имела низкий гигиенический статус. При этом индекс OHI-S в среднем равнялся 2,74 ± 0,33 у.е. (контроль – 0,50 ±  0,07 у.е.). С целью снижения негативного влияния микроорганизмов,  находящихся в на- и поддесневых зубных отложениях, всем пациентам проводилась профессиональная гигиена полости рта, а также  противомикробная терапия. На момент установки дентальных имплантатов средний уровень индекса OHI-S и Мюллеман – Коуэлла составил соответственно 0,72 ± 0,06 и 0,57 ± 0,06 у.е. </p></sec><sec><title>Выводы</title><p>Выводы. 1. Увеличение титра щелочной фосфатазы и остеокальцина при операции дентальной имплантации не является статистически  значимым. 2. ТКРФ в ротовой жидкости (слюне) проявляет максимальную активность к 14-м суткам, превышая начальную в три раза. Данный показатель сохраняется на повышенном уровне в периоде до полугода от начала операции. 3. Выявление значений титра ТРКФ после  проведения операции дентальной имплантации целесообразно  использовать в качестве оценки состояния трофических процессов,  происходящих в костной ткани.  </p></sec></abstract><trans-abstract xml:lang="en"><sec><title> Relevance</title><p> Relevance. The most important condition for a successful result of dental implantation is high-quality osseointegration of dental implants. In the literature, the issue of the quality of osseointegration is widely covered, which directly depends on the primary stability of dental implants. In the area of bone tissue remodeling, surrounding the installed dental implants, there are permanent processes of bone resorption and its restoration [1, 2]. </p><p>The aim is to reveal the reactivity of alkaline phosphatase and osteocalcin in the biological fluid (saliva) in patients after dental implants. </p></sec><sec><title>Materials and methods</title><p>Materials and methods. The collection and analysis of clinical material was carried out on the basis of the Clinics of the Samara State Medical University of the Ministry of Health of Russia. Dental implantation surgery was performed in 184 patients aged 32 to 65 years. The gender ratio was 2:3 (40 men and 60 women). The teeth were lost due to poor oral hygiene and  caries complications. </p></sec><sec><title>Results and discussion</title><p>Results and discussion. At the time of admission of patients to the department of the Department of Prosthetic Dentistry of the Clinics of the Samara State Medical University of the Ministry of Health of Russia, the bulk  of the patients had a low hygienic status. The OHI-S index averaged 2.74 ±  0.33 conventional units. (control – 0.50 ± 0.07 c.u.). In order to reduce the negative influence of microorganisms in the supra- and subgingival dental  deposits, all patients underwent professional oral hygiene, as well as  antimicrobial therapy. At the time of installation of dental implants, the average OHI-S and Müllemann-Cowell index was 0.72 ± 0.06 and 0.57 ± 0.06 conventional units, respectively. </p></sec><sec><title>Conclusions</title><p>Conclusions. 1. The increase in the titer of alkaline phosphatase and  osteocalcin during dental implantation is not statistically significant. 2. TCRF  in the oral fluid (saliva) exhibits maximum activity by the 14th day, exceeding  the initial three times. This indicator remains at an increased level  in the period up to six months from the beginning of the operation. 3. Revealing the values of the TRKF titer after the operation of dental  implantation is advisable to use as an assessment of the state of trophic  processes occurring in the bone tissue. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>дентальная имплантация</kwd><kwd>остеоинтеграция</kwd><kwd>трофика костной ткани</kwd></kwd-group><kwd-group xml:lang="en"><kwd>dental implantation</kwd><kwd>osseointegration</kwd><kwd>bone trophism</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Duarte PM, Serrão CR, Miranda TS, Zanatta LC, Bastos MF, Faveri M, Figueiredo LC, Feres M. Could cytokine levels in the peri-implant crevicular fluid be used to distinguish between healthy implants and implants with periimplantitis? A systematic review. 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