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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2022.1.CLIN.2</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-355</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая медицина</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical medicine</subject></subj-group></article-categories><title-group><article-title>Влияние индекса Глисона на выживаемость больных локализованным раком предстательной железы в Самарской области</article-title><trans-title-group xml:lang="en"><trans-title>Effect of Glison index on survival of patients with localized prostate cancer in Samara region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5385-7049</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреева</surname><given-names>Р. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreeva</surname><given-names>R. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры урологии </p><p>РИНЦ SPIN-код: 5882-3947, AuthorID: 1061971</p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><email xlink:type="simple">RaMiLyA210692@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4452-8547</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Низамова</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nizamova</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующая кафедрой урологии</p><p>РИНЦ SPIN-код: 7581-0539, AuthorID: 395334</p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><email xlink:type="simple">nizamovars@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1699-2959</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корабельников</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Korabelnikov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры урологии </p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><email xlink:type="simple">nihilius2009@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6440-793X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журкина</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhurkina</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, доцент кафедры урологии </p><p>РИНЦ SPIN-код: 6199-0713, AuthorID: 681299</p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><email xlink:type="simple">jolga006@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Самарский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>11</day><month>05</month><year>2022</year></pub-date><volume>12</volume><issue>2</issue><fpage>90</fpage><lpage>97</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Андреева Р.Д., Низамова Р.С., Корабельников А.С., Журкина О.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Андреева Р.Д., Низамова Р.С., Корабельников А.С., Журкина О.В.</copyright-holder><copyright-holder xml:lang="en">Andreeva R.D., Nizamova R.S., Korabelnikov A.S., Zhurkina O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/355">https://vestnik.reaviz.ru/jour/article/view/355</self-uri><abstract><p>Рак предстательной железы (РПЖ) находится на третьем месте по структуре смертности у мужчин. Наиболее значимым фактором, влияющим на тактику лечения и на вероятность прогрессии опухоли после радикального лечения, является степень злокачественности опухоли. Цель исследования: проанализировать влияние группы степени злокачественности аденокарциномы простаты на выживаемость больных локализованным формами на территории Самарской области. В исследование вошли пациенты с впервые диагностированным локализованным РПЖ на территории Самарской области за 2010–2016 гг. – 2535 человек, зарегистрированных в базе данных популяционного ракового регистра Самарского областного клинического онкологического диспансера. При анализе исследуемого показателя прослеживается зависимость общей и канцерспецифической выживаемости больных локализованным раком предстательной железы от степени злокачественности опухоли. У пациентов при увеличении степени злокачественности опухоли повышается риск смерти от рака простаты.</p></abstract><trans-abstract xml:lang="en"><p>Prostate cancer is in third place in the structure of mortality in men. The most significant factor influencing the tactics of treatment and the likelihood of tumor progression after radical treatment is the degree of tumor malignancy. The aim of the study was to analyze the influence of the group of grade of malignancy of prostate adenocarcinoma on the survival rate of patients with localized forms in the Samara region. The study included all patients with newly diagnosed localized prostate cancer in the Samara region in 2010–2016 – 2535 patients registered in the database of the population cancer registry of the Samara Regional Clinical Oncological Dispensary. When analyzing the investigated indicator, the dependence of the general and cancer-specific survival of patients with localized prostate cancer on the degree of tumor malignancy is traced. In patients with an increase in tumor grade, the risk of death from prostate cancer increases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак предстательной железы</kwd><kwd>выживаемость</kwd><kwd>рак простаты промежуточного риска</kwd><kwd>степень злокачественности аденокарциномы простаты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>prostate cancer</kwd><kwd>survival</kwd><kwd>intermediate-risk prostate cancer</kwd><kwd>grade of prostate cancer</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аллина Д.О., Андреева Ю.Ю., Завалишина Л.Э. и др. FASN в диагностике новообразований предстательной железы. 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