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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2022.5.CLIN</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-518</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая медицина</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical medicine</subject></subj-group></article-categories><title-group><article-title>Проблема верификации злокачественных новообразований желудка в хирургической практике</article-title><trans-title-group xml:lang="en"><trans-title>The problem of verification of malignant neoplasms of the stomach in surgical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5690-4277</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Максимов Дмитрий Анатольевич - ассистент кафедры общей хирургии.</p><p>Тверь.</p></bio><bio xml:lang="en"><p>Tver.</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9657-8063</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергеев</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergeev</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергеев Алексей Николаевич - доктор медицинских наук, доцент, заведующий кафедрой общей хирургии.</p><p>Тверь.</p></bio><bio xml:lang="en"><p>Tver.</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4213-5379</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозов Артём Михайлович - кандидат технических наук, доцент кафедры общей хирургии.</p><p>Тверь.</p><p>SPIN-код 6815-9332 </p></bio><bio xml:lang="en"><p>Tver.</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6125-7676</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беляк</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Belyak</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беляк Мария Александровна - студентка 5 курса лечебного факультета.</p><p>Тверь.</p><p>SPIN-код 5449-65802 </p></bio><bio xml:lang="en"><p>Tver.</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8708-761X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ноженко</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Nozhenko</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ноженко Елизавета Николаевна - студентка 5 курса педиатрического факультета.</p><p>Тверь.</p></bio><bio xml:lang="en"><p>Tver.</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тверской государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tver State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>18</day><month>09</month><year>2022</year></pub-date><volume>0</volume><issue>5</issue><fpage>50</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Максимов Д.А., Сергеев А.Н., Морозов А.М., Беляк М.А., Ноженко Е.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Максимов Д.А., Сергеев А.Н., Морозов А.М., Беляк М.А., Ноженко Е.Н.</copyright-holder><copyright-holder xml:lang="en">Maksimov D.A., Sergeev A.N., Morozov A.M., Belyak M.A., Nozhenko E.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/518">https://vestnik.reaviz.ru/jour/article/view/518</self-uri><abstract><p>Актуальность. Несмотря на многочисленные усилия, предпринятые в последние десятилетия, арсенал диагностики онкологических заболеваний всё ещё остается значительно ограниченным. Цель: проанализировать проблему дифференциальной диагностики ранней стадии злокачественных новообразований желудка и неонкологических заболеваний органов брюшной полости. Материалы и методы. В ходе работы были проанализированы актуальные литературные источники отечественных и зарубежных авторов по заданной теме. Результаты. Ранние стадии злокачественных новообразований желудка обычно протекают бессимптомно или сопровождаются неспецифическими признаками, такими как диспепсия. Симптомы развития злокачественных опухолей желудка на ранней стадии могут быть неотличимы от симптомов доброкачественной диспепсии, в то время как наличие установленных «тревожных» симптомов может означать прогрессирующее неоперабельное заболевание. Однако доказательства, подтверждающие использование «тревожных» симптомов в качестве критериев отбора для эндоскопии, всё же остаются противоречивыми, поскольку присутствие «тревожных» симптомов в клинической картине не всегда ассоциировано с выявлением злокачественных новообразований, также стоит отметить и то, что общая распространённость данной симптоматики в популяции пациентов, страдающих диспепсическими расстройствами, высока, в то время как численность больных, имеющих в анамнезе онкологическое заболевание ЖКТ, относительно низкая. Заключение. Несмотря на прослеживаемую тенденцию снижения заболеваемости и смертности, злокачественные новообразования желудка остаются важной проблемой в структуре онкологических заболеваний. Многие из факторов риска остаются недостаточно изученными и должны быть предметом дальнейших исследований для достижения более конкретных, целенаправленных профилактических мер.</p></abstract><trans-abstract xml:lang="en"><p>Relevance. Despite numerous efforts made in recent decades, the arsenal of cancer diagnostics is still significantly limited. The purpose of study: to analyze the problem of differential diagnosis of early stage stomach cancer and non-oncological diseases of the abdominal cavity. Materials and methods. In the course of the work, current literary sources of domestic and foreign authors on a given topic were analyzed. Results. The early stages of malignant neoplasms of the stomach are usually asymptomatic or accompanied by nonspecific signs, such as dyspepsia. Symptoms of the development of malignant tumors of the stomach at an early stage may be indistinguishable from the symptoms of benign dyspepsia, while the presence of established "alarming" symptoms may mean a progressive inoperable disease. However, the evidence supporting the use of "alarming" symptoms as selection criteria for endoscopy still remains contradictory, since the presence of "alarming" symptoms in the clinical picture is not always associated with the detection of malignant neoplasms, it is also worth noting that the overall prevalence of these symptoms in the population of patients suffering from dyspeptic disorders is high, while while the number of patients with a history of gastrointestinal cancer is relatively low. Conclusion. Despite the observed trend of decreasing morbidity and mortality, malignant neoplasms of the stomach remain an important part in the structure of oncological diseases. Many of the risk factors remain insufficiently studied and should be the subject of further research to achieve more specific, targeted preventive measures.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак желудка</kwd><kwd>злокачественные новообразования</kwd><kwd>онкология</kwd><kwd>хирургия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stomach cancer</kwd><kwd>malignant neoplasms</kwd><kwd>oncology</kwd><kwd>surgery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sung H., Ferlay J., Siegel R.L., Laversanne M., Soerjomataram I., Jemal A., Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209-249.</mixed-citation><mixed-citation xml:lang="en">Sung H., Ferlay J., Siegel R.L., Laversanne M., Soerjomataram I., Jemal A., Bray F. 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