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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2022.6.MORPH.1</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-521</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Морфология, патология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Morphology, pathology</subject></subj-group></article-categories><title-group><article-title>Вопросы диагностического поиска саркомы мягких тканей</article-title><trans-title-group xml:lang="en"><trans-title>Issues of diagnostic search of soft tissue sarcoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9657-8063</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергеев</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergeev</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергеев Алексей Николаевич - доктор медицинских наук, доцент, заведующий кафедрой общей хирургии</p><p> Тверь </p></bio><bio xml:lang="en"><p> Tver </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5690-4277</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Максимов Дмитрий Анатольевич - ассистент кафедры общей хирургии</p><p>Тверь </p></bio><bio xml:lang="en"><p> Tver </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4213-5379</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозов Артем Михайлович - кандидат медицинских наук, доцент кафедры общей хирургии</p><p>SPIN-код 6815-9332</p><p> Тверь </p></bio><bio xml:lang="en"><p> Tver </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6125-7676</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беляк</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Belyak</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беляк Мария Александровна - студентка 5 курса лечебного факультета</p><p>SPIN-код 5449-6580</p><p> Тверь </p></bio><bio xml:lang="en"><p> Tver </p></bio><email xlink:type="simple">belyakmariah@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2481-9857</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пенязь</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Penyaz'</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пенязь Екатерина Владиславовна - студентка 6 курса лечебного факультета</p><p> Тверь </p></bio><bio xml:lang="en"><p> Tver </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3096-8138</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попова</surname><given-names>М. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Popova</surname><given-names>M. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попова Мария Олеговна - студентка 6 курса лечебного факультета</p><p> Тверь </p></bio><bio xml:lang="en"><p> Tver </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тверской государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tver State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>18</day><month>11</month><year>2022</year></pub-date><volume>12</volume><issue>6</issue><fpage>15</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сергеев А.Н., Максимов Д.А., Морозов А.М., Беляк М.А., Пенязь Е.В., Попова М.О., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Сергеев А.Н., Максимов Д.А., Морозов А.М., Беляк М.А., Пенязь Е.В., Попова М.О.</copyright-holder><copyright-holder xml:lang="en">Sergeev A.N., Maksimov D.A., Morozov A.M., Belyak M.A., Penyaz' E.V., Popova M.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/521">https://vestnik.reaviz.ru/jour/article/view/521</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Саркома мягких тканей представляет собой гетерогенную группу относительно редких видов опухолей, которая демонстрирует огромное разнообразие анатомических локализаций и гистопатологических характеристик. Редкость сарком мягких тканей в сочетании с разнообразием подтипов, формами роста, прогрессирования и частотой рецидивов затрудняет их изучение, постановку правильного диагноза и раннее направление пациентов для специализированной помощи.</p></sec><sec><title>Цель</title><p>Цель: изучить подходы к дифференциальной диагностике злокачественных и доброкачественных новообразований мягких тканей.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В ходе работы были проанализированы актуальные литературные источники отечественных и зарубежных авторов на заданную тему.</p></sec><sec><title>Результаты</title><p>Результаты. Поскольку абсолютно точно не представляется возможным определить клинические особенности представленной саркомы, опухоли мягких тканей, проявляющие любой из следующих признаков, считаются злокачественными, пока не будет доказано обратное: увеличение в размерах, размер более 5 см, глубокое расположение и/или болезненность. Чем больше число данных клинических признаков присутствует, тем выше риск того, что опухоль мягких тканей окажется злокачественной, при этом увеличение размера является преимущественным индивидуальным показателем. Стоит отметить, что отсутствие сопутствующих конституциональных симптомов, таких как лихорадка, озноб, ночная потливость или непреднамеренная потеря веса, не должно снижать уровень подозрения врача на злокачественность.</p></sec><sec><title>Заключение</title><p>Заключение. Чтобы избежать ошибочных диагнозов, следует придерживаться стандартизированного диагностического подхода начиная с момента сбора анамнеза, клинического обследования и заканчивая использованием соответствующих методов визуализации и проведением цитологического исследования.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Soft tissue sarcoma is a heterogeneous group of relatively rare types of tumors, which demonstrates a huge variety of anatomical localization and histopathological characteristics. The rarity of soft tissue sarcomas combined with a variety of subtypes, forms of growth, progression and frequency of relapses makes it difficult to study them, make a correct diagnosis and early referral of patients for specialized care.</p></sec><sec><title>The purpose of study</title><p>The purpose of study. To analyze the problem of differential diagnosis of malignant and benign soft tissue neoplasms.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. In the course of the work, current literary sources of domestic and foreign authors on a given topic were analyzed.</p></sec><sec><title>Results</title><p>Results. Since it is absolutely impossible to determine the clinical features of the presented sarcoma, soft tissue tumors showing any of the following signs are considered malignant until the opposite is proven: increasing in size, &gt;5 cm, deeply located and/or painful. The greater the number of these clinical signs present, the higher the risk that the soft tissue tumor will turn out to be malignant; at the same time, an increase in size is the best individual indicator. It is worth noting that the absence of concomitant constitutional symptoms, such as fever, chills, night sweats or unintentional weight loss, should not reduce the doctor's suspicion of malignancy.</p></sec><sec><title>Conclusion</title><p>Conclusion. In order to avoid erroneous diagnoses, a standardized diagnostic approach should be followed, starting from the moment of collecting the patient's medical history, clinical examination and ending with the use of appropriate imaging methods and biopsy.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>саркома мягких тканей</kwd><kwd>онкология</kwd><kwd>хирургия</kwd><kwd>злокачественные новообразования</kwd><kwd>верификация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>soft tissue sarcoma</kwd><kwd>oncology</kwd><kwd>surgery</kwd><kwd>malignant neoplasms</kwd><kwd>verification</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бенберин В.В., Байзаков Б.Т., Шаназаров Н.А., Зинченко С.В. Саркомы мягких тканей: современный взгляд на проблему. 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