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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2023.5.CASE.4</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-837</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинический случай</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical case</subject></subj-group></article-categories><title-group><article-title>Эволюция формирования полости при нетуберкулёзном микобактериозе лёгких</article-title><trans-title-group xml:lang="en"><trans-title>Evolution of cavity formation in nontuberculosis mycobacteriosis of the lungs</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8760-1164</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амансахедов</surname><given-names>Р. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Amansakhedov</surname><given-names>R. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Амансахедов Расул Бердиевич - д-р мед. наук, ведущий научный сотрудник,</p><p>Яузская аллея, д. 2, Москва, 107564</p></bio><bio xml:lang="en"><p>Rasul B. Amansakhedov - Doctor of Medical Sciences, leading researcher,</p><p>2 Yauzskaya Alley, 2, Moscow, 107564</p></bio><email xlink:type="simple">rasul.amansahedov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6390-8759</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарьянц</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Makar'yants</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Макарьянц Наталья Николаевна - д-р мед. наук, ведущий научный сотрудник, руководитель отдела дифференциальной диагностики туберкулёза лёгких и экстракорпоральных методов лечения,</p><p>Яузская аллея, д. 2, Москва, 107564</p></bio><bio xml:lang="en"><p>Natal'ya N. Makar'yants - Doctor of Medical Sciences, Leading researcher, Head of the Department of Differential Diagnosis of Pulmonary Tuberculosis and extra-corporeal methods of treatment,</p><p>2 Yauzskaya Alley, 2, Moscow, 107564</p></bio><email xlink:type="simple">makaryantz@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5267-7193</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисова</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisova</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Борисова Анастасия Юрьевна - врач-рентгенолог,</p><p>Яузская аллея, д. 2, Москва, 107564</p></bio><bio xml:lang="en"><p>Anastasiya Y. Borisova - Radiologist,</p><p>2 Yauzskaya Alley, 2, Moscow, 107564</p></bio><email xlink:type="simple">anastasiyadudko88@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-4851-9125</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белова</surname><given-names>У. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Belova</surname><given-names>U. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белова Ульяна Владимировна - врач-рентгенолог,</p><p>Яузская аллея, д. 2, Москва, 107564</p></bio><bio xml:lang="en"><p>Ul'yana V. Belova - Radiologist,</p><p>2 Yauzskaya Alley, 2, Moscow, 107564</p></bio><email xlink:type="simple">ulyana-kotelnikova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6894-2411</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лепеха</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lepekha</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лепеха Лариса Николаевна - д-р мед. наук, профессор, главный научный сотрудник отдела патоморфологии, клеточной биологии и биохимии,</p><p>Яузская аллея, д. 2, Москва, 107564</p></bio><bio xml:lang="en"><p>Larisa N. Lepekha - Dr. Sci. (Med.), Professor, Chief Researcher of the Department of Pathomorphology, Cell Biology and Biochemistry,</p><p>2 Yauzskaya Alley, 2, Moscow, 107564</p></bio><email xlink:type="simple">lep3@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9337-3903</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпина</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpina</surname><given-names>N. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карпина Наталья Леонидовна - д-р мед. наук, заместитель директора по научной работе, руководитель Центра диагностики и реабилитации заболеваний органов дыхания,</p><p>Яузская аллея, д. 2, Москва, 107564</p></bio><bio xml:lang="en"><p>Natal'ya L. Karpina - Doctor of Medical Sciences, Deputy Director for Scientific Work, Head of the Center for Diagnosis and Rehabilitation of Respiratory Diseases,</p><p>2 Yauzskaya Alley, 2, Moscow, 107564</p></bio><email xlink:type="simple">natalya-karpina@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Центральный научно-исследовательский институт туберкулёза</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Tuberculosis</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>05</day><month>09</month><year>2023</year></pub-date><volume>13</volume><issue>5</issue><fpage>137</fpage><lpage>141</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Амансахедов Р.Б., Макарьянц Н.Н., Борисова А.Ю., Белова У.В., Лепеха Л.Н., Карпина Н.Л., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Амансахедов Р.Б., Макарьянц Н.Н., Борисова А.Ю., Белова У.В., Лепеха Л.Н., Карпина Н.Л.</copyright-holder><copyright-holder xml:lang="en">Amansakhedov R.B., Makar'yants N.N., Borisova A.Y., Belova U.V., Lepekha L.N., Karpina N.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/837">https://vestnik.reaviz.ru/jour/article/view/837</self-uri><abstract><p>Приводятся результаты длительного наблюдения из практики, показавшего поэтапное формирования полости деструкции у пациента с ограниченным очаговым и перибронхиальным фиброзом лёгочной ткани. Пациентка Х., 54 года, на протяжении более 20 лет наблюдалась у пульмонолога по месту жительства с диагнозом: хронический бронхит с частыми ежегодными обострениями. Поступила в клинику ФГБНУ «ЦНИИТ» с жалобами на выраженную слабость, утомляемость, одышку, длительно сохраняющуюся субфебрильную температуру преимущественно в ночное время, кашель с трудноотделяемой мокротой слизистого характера. При ретроспективном анализе данных компьютерной томографии органов грудной клетки установлено последовательная трансформация локального очагово-перибронхиального уплотнения в средней доле правого лёгкого в ограниченный участок бронхоэктазии и формирование небольшой кистозной полости с распространёнными зонами билатеральной пневмонической инфильтрации. Данное наблюдение показывает практическую значимость КТ исследования в понимании механизмов формирования бронхоэктатической кистозной полости при нетуберкулёзных микобактериозах лёгких.</p></abstract><trans-abstract xml:lang="en"><p>The results of a long – term observation from practice are presented, which showed the gradual formation of the destruction cavity in a patient with limited focal and peribronchial fibrosis of the lung tissue. Patient H., 54 years old for more than twenty years, was observed by a pulmonologist at the place of residence with a diagnosis of chronic bronchitis with frequent annual exacerbations. She was admitted to the clinic of the FSBSI "CRIT" with complaints of pronounced weakness, fatigue, shortness of breath, prolonged subfebrile temperature mainly at night, cough with difficult-to-separate mucus of a mucous nature. A retrospective analysis of computed tomography of the chest revealed a consistent transformation of local focal peribronchial compaction in the middle lobe of the right lung into a limited area of bronchiectasia and the formation of a small cystic cavity with widespread zones of bilateral pneumonic infiltration. This observation shows the practical significance of CT research in understanding the mechanisms of formation of bronchiectatic cystic cavity in non-tuberculosis mycobacteriosis of the lungs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>компьютерная томография</kwd><kwd>нетуберкулёзный микобактериоз лёгких</kwd><kwd>кистозная полость</kwd></kwd-group><kwd-group xml:lang="en"><kwd>computed tomography</kwd><kwd>non-tuberculosis mycobacteriosis of the lungs</kwd><kwd>cystic cavity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cole PJ. 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