vmireavizВестник медицинского института «РЕАВИЗ». Реабилитация, Врач и ЗдоровьеBulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)2226-762X2782-1579РЕАВИЗ10.20340/vmi-rvz.2020.4.8vmireaviz-84Research ArticleКлиническая медицинаClinical medicineМитохондриальные изменения в канцерогенезе как цель противоопухолевой терапии (обзор)Mitochondrial changes in carcinogenesis as a goal of antitumor therapy (review)ПотеминаТ. Е.PoteminaT. E.

Потемина Татьяна Евгеньевна - доктор медицинских наук, профессор, заведующий кафедрой патологической физиологии

Нижний Новгород

Nizhny Novgorod

ГузиковЭ. В.GuzikovE. V.

Гузиков Эдуард Валерьевич - ассистент кафедры патологической физиологии; врач анестезиолог реаниматолог отделения реанимации и интенсивной терапии для новорожденных

Нижний Новгород

Nizhny Novgorod

ФГБОУ ВО «Приволжский исследовательский медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Institution of Higher Education «Volga Medical Research University» Ministry ofHealth of the Russian FederationRussian FederationФГБОУ ВО «Приволжский исследовательский медицинский университет» Министерства здравоохранения Российской Федерации; ГБУЗ НО «Нижегородская областная детская клиническая больница»РоссияFederal State Budgetary Institution of Higher Education «Volga Medical Research University» Ministry of Health of the Russian Federation; GBUZ NO «Nizhny Novgorod Regional Children's Clinical Hospital»Russian Federation202031122020046573Copyright © Потемина Т.Е., Гузиков Э.В., 20202020Потемина Т.Е., Гузиков Э.В.Potemina T.E., Guzikov E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestnik.reaviz.ru/jour/article/view/84

Причины и механизмы развития рака в настоящее время являются одной из актуальных проблем медицины. Основным вариантом на сегодняшний день является мутационная теория. Выявление системы генных мутаций, в том числе и в митохондриях, приводящих к тому или иному виду опухолей, сделали возможным разработку персонализированной так называемой таргетной терапии злокачественных опухолей.

Causes and mechanisms of cancer development are currently one of the urgent problems of medicine. The main variant for today is the mutation theory. Identification of the system of gene mutations, including in mitochondria, leading to this or that type of tumors, made it possible to develop a personalized, so-called targeting, the therapy of malignant tumors.

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The authors declare that there are no conflicts of interest present.