vmireavizВестник медицинского института «РЕАВИЗ». Реабилитация, Врач и ЗдоровьеBulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)2226-762X2782-1579РЕАВИЗ10.20340/vmi-rvz.2024.2.MIM.1vmireaviz-882Research ArticleМедицинская визуализацияMedical ImagingМетоды лучевой визуализации в диагностике хронических заболеваний печениMethods of radiology in the diagnostics of chronic liver diseaseshttps://orcid.org/0000-0002-8258-522XСавченковЮ. Н.SavchenkovYu. N.

Савченков Юрий Николаевич, Канд. мед. наук, ассистент кафедры лучевой диагностики с курсом радиологии; заведующий отделением лучевой диагностики

ул. Маршала Новикова, д. 23, г. Москва, 123098

ул. Велозаводская, д. 1/1, г. Москва, 115280

Yuriy N. Savchenkov, Cand. Sci. (Med.), Assistant of the Department of Radiation Diagnostics with a course in Radiology; Head of the Department of Radiation Diagnostics

23, Marshal Novikov str., Moscow, 123098

1/1, Velozavodskaya str., Moscow, 115280

yura_savchenkov@mail.ruhttps://orcid.org/0000-0002-1611-5000ТруфановГ. Е.TrufanovG. E.

Труфанов Геннадий Евгеньевич, Д-р мед. наук, профессор, заведующий кафедрой лучевой диагностики и медицинской визуализации

ул. Аккуратова, д. 2, г. Санкт-Петербург, 197341

Gennadiy E. Trufanov, Dr. Sci. (Med.), Professor, Head of the Department of Radiation Diagnostics and Medical Imaging

2, Akkuratova str., St. Petersburg, 197341

trufanovge@mail.ruhttps://orcid.org/0000-0002-2937-6322ФокинВ. А.FokinV. A.

Фокин Владимир Александрович, Д-р мед. наук, профессор кафедры лучевой диагностики и медицинской визуализации

ул. Аккуратова, д. 2, г. Санкт-Петербург, 197341

Vladimir A. Fokin, Dr. Sci. (Med.), Professor of the Department of Radiation Diagnostics and Medical Imaging

2, Akkuratova str., St. Petersburg, 197341

vladfokin@mail.ruhttps://orcid.org/0000-0002-6084-2061ИоноваЕ. А.IonovaE. A.

Ионова Елена Александровна, Д-р мед. наук, заведующий кафедрой лучевой диагностики с курсом радиологии

ул. Маршала Новикова, д. 23, г. Москва, 123098

Elena A. Ionova, Dr. Sci. (Med.), Head of the Department of Radiation Diagnostics with a course in Radiology

23, Marshal Novikov str., Moscow, 123098

ionela60@mail.ruhttps://orcid.org/0000-0003-3911-8543АракеловС. Э.ArakelovS. E.

Аракелов Сергей Эрнестович, Д-р мед. наук, профессор, заведующий кафедрой «Семейная медицина с курсом паллиативной медицинской помощи»; главный врач

ул. Велозаводская, д. 1/1, г. Москва, 115280

ул. Миклухо-Маклая, д. 6, г. Москва, 117198

Sergey E. Arakelov, Dr. Sci. (Med.), Professor, Head of the Department of Family Medicine with a Course of Palliative Care, Chief Physician

1/1, Velozavodskaya str., Moscow, 115280

6, Miklukho-Maklay str., Moscow, 117198

arakelov-s@yandex.ruhttps://orcid.org/0000-0001-7056-0634ТитоваИ. Ю.TitovaI. Yu.

Титова Ирина Юрьевна, Заместитель главного врача по медицинской части

ул. Велозаводская, д. 1/1, г. Москва, 115280

Irina Yu. Titova, Deputy Chief Medical Officer

1/1, Velozavodskaya str., Moscow, 115280

titovaiy1@zdrav.mos.ruhttps://orcid.org/0000-0003-2249-1405ЕфимцевА. Ю.EfimtsevA. Yu.

Ефимцев Александр Юрьевич, Д-р мед. наук, доцент кафедры лучевой диагностики и медицинской визуализации

ул. Аккуратова, д. 2, г. Санкт-Петербург, 197341

Aleksandr Yu. Efimtsev, Dr. Sci. (Med.), Associate Professor of the Department of Radiation Diagnostics and Medical Imaging

2, Akkuratova str., St. Petersburg, 197341

atralf@mail.ruhttps://orcid.org/0000-0002-5149-4667МелтонянА. Р.MeltonyanA. R.

Мелтонян Ася Робертовна, Аспирант кафедры эндокринологии

ул. Аккуратова, д. 2, г. Санкт-Петербург, 197341

Asya R. Meltonyan, Postgraduate Student of Department of Endocrinology

2, Akkuratova str., St. Petersburg, 197341

a.r.meltonyan@yandex.ruГосударственный научный центр Российской Федерации – Федеральный медицинский биофизический центр имени А.И. Бурназяна; Городская клиническая больница № 13РоссияState Scientific Center of the Russian Federation – A. I. Burnazyan Federal Medical Biophysical Center; City Clinical Hospital No. 13Russian FederationНациональный медицинский исследовательский центр имени В.А. АлмазоваРоссияNational Medical Research Centre named after V.A. AlmazovRussian FederationГосударственный научный центр Российской Федерации – Федеральный медицинский биофизический центр имени А.И. БурназянаРоссияState Scientific Center of the Russian Federation - A. I. Burnazyan Federal Medical Biophysical CenterRussian FederationГородская клиническая больница № 13; Российский университет дружбы народов имени Патриса ЛумумбыРоссияCity Clinical Hospital No. 13; Patrice Lumumba Peoples' Friendship University of RussiaRussian FederationГородская клиническая больница № 13РоссияCity Clinical Hospital No. 13Russian Federation202410032024142111122Copyright © Савченков Ю.Н., Труфанов Г.Е., Фокин В.А., Ионова Е.А., Аракелов С.Э., Титова И.Ю., Ефимцев А.Ю., Мелтонян А.Р., 20242024Савченков Ю.Н., Труфанов Г.Е., Фокин В.А., Ионова Е.А., Аракелов С.Э., Титова И.Ю., Ефимцев А.Ю., Мелтонян А.Р.Savchenkov Y.N., Trufanov G.E., Fokin V.A., Ionova E.A., Arakelov S.E., Titova I.Y., Efimtsev A.Y., Meltonyan A.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestnik.reaviz.ru/jour/article/view/882Актуальность

Актуальность. Хронические заболевания печени являются одними из самых распространённых поражений органов и систем, входящие во многих странах в первую пятерку причин смертности. Печень является одним из основных органов, ответственных за ключевые функции обмена веществ, синтеза белков и гормонов, детоксикации и выведения отходов. При хронических заболеваниях печени происходит непрерывный процесс воспаления, разрушения и регенерации, в конечном итоге приводящий к выраженному нарушению функций печени вследствие развития фиброза и цирроза. Главной задачей лучевой диагностики хронических заболеваний печени является разработка и внедрение в клиническую практику новых неинвазивных биомаркеров для всесторонней оценки структуры паренхимы печени с целью выбора дальнейшей тактики лечения.

Цель

Цель: всесторонний анализ современных возможностей методов лучевой визуализации в диагностике хронических заболеваний печени.

Материалы и методы

Материалы и методы. Произведён анализ 107 современных публикаций отечественной и зарубежной литературы, посвящённых диагностике хронических заболеваний печени различной этиологии.

Заключение

Заключение. В статье отражены наиболее распространённые современные и перспективные методики лучевой визуализации при хронических заболеваниях печени, которые, в большинстве случаев, позволяют отказаться от инвазивных вмешательств в процессе установки диагноза и мониторинге ответа на проводимое лечение. 

Background

Background. Chronic liver disease is one of the most common diseases. In many countries, liver disease is among the top five causes of death. The liver is one of the main organs responsible for basic metabolic functions, protein and hormone synthesis, detoxification and waste elimination. In chronic liver disease, there is a continuous process of inflammation, destruction and regeneration, ultimately leading to severe dysfunction, causing the development of fibrosis and cirrhosis. The main task of the radiation diagnosis of chronic liver disease is the development and introduction into clinical practice of new noninvasive biomarkers for a comprehensive assessment of the structure of the liver parenchyma in order to choose further treatment tactics.

Aim a comprehensive analysis of the modern possibilities of radiation imaging methods in the diagnosis of chronic liver disease.

Materials and methods

Materials and methods. The analysis of 107 modern publications of domestic and foreign literature devoted to the diagnosis of chronic liver disease  of various etiologies was carried out.

Conclusion

Conclusion. the review reflects the most common modern and promising methods of radiodiagnosis for chronic liver disease, which in most cases make it possible to avoid invasive interventions in the process of establishing a diagnosis and monitoring the response to treatment

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The authors declare that there are no conflicts of interest present.