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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vmireaviz</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник медицинского института «РЕАВИЗ». Реабилитация, Врач и Здоровье</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2226-762X</issn><issn pub-type="epub">2782-1579</issn><publisher><publisher-name>РЕАВИЗ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20340/vmi-rvz.2023.6.CLIN.17</article-id><article-id custom-type="elpub" pub-id-type="custom">vmireaviz-886</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая медицина</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical medicine</subject></subj-group></article-categories><title-group><article-title>Сравнительная оценка способов хирургического лечения хронического панкреатита. Обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>Surgical treament of chronic pancreatitis (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0720-9934</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозов Сергей Валентинович - Д-р мед. наук, ведущий научный сотрудник отделения абдоминальной хирургии.</p><p>Ул. Щепкина, д. 61/2, Москва, 129110</p></bio><bio xml:lang="en"><p>Sergey V. Morozov - Dr. Sci., Leading Researcher, Department of Abdominal Surgery.</p><p>61/2, Shchepkina str., Moscow, 129110</p></bio><email xlink:type="simple">msv150362@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2363-0235</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Румянцев</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Rumyantsev</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Румянцев Вячеслав Борисович - Канд. мед. наук, заведующий 1 хирургическим отделением.</p><p>Ул. Щепкина, д. 61/2, Москва, 129110</p></bio><bio xml:lang="en"><p>Vyacheslav B. Rumyantsev - Candidate of Medical Sciences, Head of the 1st Surgical Department.</p><p>61/2, Shchepkina str., Moscow, 129110</p></bio><email xlink:type="simple">v.rumyansev@monikiweb.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7661-5528</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобаков</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Lobakov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лобаков Александр Иванович - Д-р мед. наук, профессор кафедры хирургии.</p><p>Ул. Щепкина, д. 61/2, Москва, 129110</p></bio><bio xml:lang="en"><p>Aleksandr I. Lobakov - Dr. Sci., Professor of the Department of Surgery of the Federal University of Higher Education.</p><p>61/2, Shchepkina str., Moscow, 129110</p></bio><email xlink:type="simple">lobakovmoniki@gmail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2845-1703</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербюк</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcherbyuk</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Щербюк Александр Николаевич - Д-р мед. наук, профессор кафедры хирургии.</p><p>Ул. Щепкина, д. 61/2, Москва, 129110</p></bio><bio xml:lang="en"><p>Aleksandr N. Shcherbyuk - Dr. Sci., Professor of the Department of Surgery of the Federal University of Higher Education.</p><p>61/2, Shchepkina str., Moscow, 129110</p></bio><email xlink:type="simple">ANS1949@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3796-5530</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Флегонтов</surname><given-names>П. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Flegontov</surname><given-names>P. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Флегонтов Петр Борисович - младший научный сотрудник отделения абдоминальной хирургии.</p><p>Ул. Щепкина, д. 61/2, Москва, 129110</p></bio><bio xml:lang="en"><p>Petr B. Flegontov - Junior Researcher, Department of Abdominal Surgery.</p><p>61/2, Shchepkina str., Moscow, 129110</p></bio><email xlink:type="simple">flegontov1991@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Research Clinical Institute named after M.F. Vladimirsky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>14</day><month>01</month><year>2024</year></pub-date><volume>13</volume><issue>6</issue><fpage>137</fpage><lpage>143</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Морозов С.В., Румянцев В.Б., Лобаков А.И., Щербюк А.Н., Флегонтов П.Б., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Морозов С.В., Румянцев В.Б., Лобаков А.И., Щербюк А.Н., Флегонтов П.Б.</copyright-holder><copyright-holder xml:lang="en">Morozov S.V., Rumyantsev V.B., Lobakov A.I., Shcherbyuk A.N., Flegontov P.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik.reaviz.ru/jour/article/view/886">https://vestnik.reaviz.ru/jour/article/view/886</self-uri><abstract><p>Цель: обобщить имеющиеся литературные данные о способах оперативного лечения хронического панкреатита, оценить их результаты, выявить недостатки и возможные пути их решения.Материалы и методы. Мы провели литературный обзор научных трудов за последние 20 лет, используя ресурсы поисковых систем PubMed, Cyberleninka и eLIBRARY, по имеющимся способам оперативного лечения хронического панкреатита. Для данного мета-анализа мы использовали статьи, содержащие доказательную экспериментальную и клиническую базу по вопросам, касающихся отдалённых и ближайших результатов оперативного лечения.Результаты и осуждение. Мы проанализировали ближайшие и отдалённые результаты способов хирургического лечения хронического панкреатита. Практически во всех исследованиях резекционно-дренирующие методы позволяли эффективно купировать болевой синдром на протяжении длительного времени. Однако экзои эндосекреторная недостаточность в большинстве случаев сохранялась или прогрессировала, независимо от применяемого метода. Ещё одним недостатком существующих способов являлось отсутствие возможности купировать кровотечение из области панкреатоеюноанастомоза в раннем послеоперационном периоде, поэтому летальность после развития данных осложнений составляла от 5 до 60 %.Заключение. На основании изученных результатов мы выделили следующие недостатки известных способов хирургического лечения хронического панкреатита: 1. Выключенная из пищеварения длинная петля тонкой кишки, не менее 70 см, приводящая к значительному уменьшению длины кишечной трубки и, соответственно, площади всасывания пищевых нутриентов. 2. Особенности реконструктивного этапа операции не обеспечивают физиологического поступления панкреатического секрета в двенадцатиперстную кишку и, соответственно, активации ферментов, тем самым отключая дуоденальную фазу пищеварения. 3. Выключенная по Ру петля тонкой кишки создаёт благоприятные условия для развития избыточного бактериального роста. 4. Отсутствие возможности эндоскопической оценки поджелудочной железы с целью остановки кровотечения в раннем послеоперационном периоде. Проанализировав данные литературы мы пришли к выводу, что устранение данных недостатков позволит улучшить результаты лечения хронического панкреатита.</p></abstract><trans-abstract xml:lang="en"><sec><title>Target</title><p>Target. To summarize the available literature data on the methods of surgical treatment of chronic pancreatitis, evaluate their results, identify shortcomings and possible solutions.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. We conducted a literature review of scientific papers over the past 20 years, using the resources of the search engines PubMed, Cyberleninka and eLIBRARY, on the available methods of surgical treatment of chronic pancreatitis. For this meta-analysis, we used articles containing an evidence-based experimental and clinical base on issues related to long-term and immediate results of surgical treatment.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. We analyzed the immediate and long-term results of the methods of surgical treatment of chronic pancreatitis. In almost all studies, resection-drainage methods made it possible to effectively stop the pain syndrome for a long time. However, exoand endocrine insufficiency in most cases persisted or progressed, regardless of the method used. Another disadvantage of the existing methods was the inability to stop bleeding from the area of pancreatojejunostomy in the early postoperative period, so mortality after the development of these complications ranged from 5 to 60%.</p></sec><sec><title>Conclusion</title><p>Conclusion. Based on the results studied, we identified the following disadvantages of the known methods of surgical treatment of chronic pancreatitis: 1. A long loop of the small intestine, at least 70 cm, turned off from digestion, leading to a significant decrease in the length of the intestinal tube, and, accordingly, the area of absorption of food nutrients. 2. The features of the reconstructive stage of the operation do not provide the physiological flow of pancreatic secretion into the duodenum and, accordingly, the activation of enzymes, thereby turning off the duodenal phase of digestion. 3. Roux-enabled loop of the small intestine creates favorable conditions for the development of excessive bacterial growth. 4. Lack of endoscopic evaluation of the pancreas to stop bleeding in the early postoperative period. After analyzing the literature data, we came to the conclusion that the elimination of these shortcomings will improve the results of chronic pancreatitis treatment.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический панкреатит</kwd><kwd>синдром избыточного бактериального роста</kwd><kwd>поджелудочная железа</kwd><kwd>резекционно-дренирующий хирургический способ</kwd><kwd>внешнесекреторная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pancreatitis</kwd><kwd>bacterial overgrowth syndrome</kwd><kwd>pancreas</kwd><kwd>surgical resection-drainage method</kwd><kwd>exocrine insufficiency</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование проводилось без спонсорской поддержки</funding-statement><funding-statement xml:lang="en">This research received no external funding</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Краснов К.А., Анищенко В.В., Пугачев С.В. 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