A case of cervical leiomyomatosis diagnosis in a patient with endometrioid carcinoma of the uterine corpus
https://doi.org/10.20340/vmi-rvz.2024.4.MORPH.3
Abstract
Leiomyomatosis is a rare tumor of smooth muscle cells with uncertain malignant potential. The available literature describes mainly cases of leiomyomatosis of the uterine body, lungs, vessels, and peritoneum. There are data on isolated cases of cervical leiomyomatosis. Most often, leiomyomatosis is asymptomatic, however, there are localizations with the development of such clinical manifestations as infertility or respiratory failure. A clinical observation of a 61-year-old patient who was diagnosed with endometrioid carcinoma, for which videoendoscopic extirpation of the uterus with appendages was performed, is presented. During the examination of the surgical material, cervical leiomyomatosis was diagnosed in the cervix. This case is of interest due to the rarity of this pathology and the complexity of its diagnosis.
About the Authors
T. A. Garkusha
Krasnoyarsk State Medical University named after Professor V. F. Voyno-Yasenetsky;
Krasnoyarsk Regional Pathological Anatomy Bureau
Russian Federation
Russian Federation
Tat'yana A. Garkusha, Assistant of the Department of Pathological Anatomy named after Professor P.G. Podzolkov, Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky; pathologist, Krasnoyarsk Regional Pathological Anatomy Bureau
1, Partizana Zheleznyaka str., Krasnoyarsk, 660022,
3D, Partizana Zheleznyaka str., Krasnoyarsk, 660022
V. N. Shelepova
Krasnoyarsk State Medical University named after Professor V. F. Voyno-Yasenetsky
Russian Federation
Russian Federation
Victoriya N. Shelepova, Student of the Pediatrics Department
1, Partizana Zheleznyaka str., Krasnoyarsk, 660022
A. N. Zagrebel'nikova
Krasnoyarsk State Medical University named after Professor V. F. Voyno-Yasenetsky
Russian Federation
Russian Federation
Aleksandra N. Zagrebel'nikova, Student of the Faculty of Pediatrics
1, Partizana Zheleznyaka str., Krasnoyarsk, 660022
D. V. Telyashkin
Krasnoyarsk Regional Clinical Oncology Dispensary named after A. I. Kryzhanovsky
Russian Federation
Russian Federation
Dmitriy V. Telyashkin, Obstetrician
16, 1-ya Smolenskaya str., Krasnoyarsk, 660133
L. G. Levkovich
Krasnoyarsk State Medical University named after Professor V. F. Voyno-Yasenetsky
Russian Federation
Russian Federation
Lyubov' G. Levkovich, Cand. Sci. (Med.), Associate Professor of the Department of Pathologi- cal Anatomy named after Professor P.G. Podzolkov
1, Partizana Zheleznyaka str., Krasnoyarsk, 660022
References
1. Morgan ED, Kahiye M, Kule I, Yahaya JJ, Othieno E. Disseminated peritoneal leiomyomatosis as an incidental finding: A case report. Clin Case Rep. 2022 Mar;10(3):e05541. https://doi.org/10.1002/ccr3.5541
2. Lee S, Kim DK, Narm KS, Cho SH. Pulmonary artery embolization of intravenous leiomyomatosis extending into the right atrium. Korean J Thorac Cardiovasc Surg. 2011 Jun; 44(3):243 – 6. https://doi.org/10.5090/kjtcs.2011.44.3.243
3. Araujo NM, Cardoso IMDS, Jatoba TKADS, et al. Rare manifestation of pulmonary benign metastasizing leiomyoma: Respiratory failure. Respir Med Case Rep. 2024;50:102053. https://doi.org/10.1016/j.rmcr.2024.102053
4. Thomas EO, Gordon J, Smith-Thomas S, Cramer SF. Diffuse uterine leiomyomatosis with uterine rupture and benign metastatic lesions of the bone. Obstet Gynecol. 2007 Feb;109(2 Pt2):528-30. https://doi.org/10.1097/01.AOG.0000237314.07944.32
5. Baschinsky DY, Isa A, Niemann TH, Prior TW, Lucas JG, Frankel WL. Diffuse leiomyomatosis of the uterus: a case report with clonality analysis. Hum Pathol. 2000 Nov;31(11):1429 – 32. https://pubmed.ncbi.nlm.nih.gov/11112221/
6. Prasad I, Sinha S, Sinha U, Kumar T, Singh J. Diffuse Leiomyomatosis of the Uterus: A Diagnostic Enigma. Cureus. 2022 Sep 26;14(9):e29595. https://doi.org/10.7759/cureus.29595
7. Mantovani M, Neto J, Philbert P, Casartelli C. Multiple Uterine Leiomyomas: Cytogenetic Analysis. Gynecol Oncol. 1999 Jan;72(1):71 – 5. https://doi.org/doi:10.1006/gyno.1998.5222
8. Hashimoto K, Azuma C, Kamiura S, Kimura T, Nobunaga T, Kanai T. Clonal Determination of Uterine Leiomyomas by Analyzing Differential Inactivation of the X-Chromosome-Linked Phosphoglycerokinase Gene. Gynecol Obstet Invest. 1995;40(3):204 – 208. https://doi.org/doi:10.1159/000292336
9. Williams ARW. Uterine fibroids – what’s new? F1000Res. 2017 Dec 7;6:2109. https://doi.org/10.12688/f1000research.12172.1
10. Kumar D, Thakur VBS, M S. Diffuse Uterine Leiomyomatosis: A Rare Case of Symmetrically Enlarged Uterus. Cureus. 2024 22 May;16(5):e60827. https://doi.org/doi:10.7759/cureus.60827
11. Ren HM, Wang QZ, Wang JN, et al. Diffuse uterine leiomyomatosis: A case report and review of literature. World J Clin Cases. 2022 Aug 26;10(24): 8797 – 8804. https://doi.org/10.12998/wjcc.v10.i24.8797
12. Wu Z, Ruan F, Niu X, Zhou J. Diffuse leiomyomatosis of the cervix: a rare tumor in a rare location. A first report and literature analysis. Clin. Exp. Obstet. Gynecol. 2019 June 10;3: 492 – 493. https://doi.org/10.12891/ceog4623.2019
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For citations:
Garkusha T.A., Shelepova V.N., Zagrebel'nikova A.N., Telyashkin D.V., Levkovich L.G. A case of cervical leiomyomatosis diagnosis in a patient with endometrioid carcinoma of the uterine corpus. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2024;14(4):20-23. (In Russ.) https://doi.org/10.20340/vmi-rvz.2024.4.MORPH.3
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