Cranioplasty with autograft and bone grafting material: a clinical case study
https://doi.org/10.20340/vmi-rvz.2023.3.CLIN7
Abstract
A clinical study of the effectiveness of delayed cranioplasty with an autologous bone flap using allogenic bone grafting material was performed. The autograft was preserved, saturated with human collagen type 1, lyophilized and sterilized. Bone-plastic material was used to fill diastases. The patient was followed up in the postoperative period for 24 months. No clinical complications were registered. Radiological and radioisotope analysis showed normal fixation of the autograft after 6, 12 and 24 months. Biopsy analysis after 12 months showed the presence of regenerative processes in the absence of inflammation. The clinical result was assessed as successful.
About the Authors
A. A. OfitserovRussian Federation
Andrey A. Ofitserov, Surgeon
3 Bolshaya Sukharevskaya Square, Moscow, 129090
N. V. Borovkova
Russian Federation
Natal'ya V. Borovkova, Dr. Sci. (Med.), Head of the Scientific Department of Biotechnology and Transfusiology
3 Bolshaya Sukharevskaya Square, Moscow, 129090
A. E. Talypov
Russian Federation
Aleksandr E. Talypov, Dr. Sci. (Med.), Neurosurgeon, Leading Researcher
3 Bolshaya Sukharevskaya Square, Moscow, 129090
M. S. Makarov
Russian Federation
Maksim S. Makarov, Cand. Sci. (Biol.), Senior Researcher at the Department of Biotechnology and Transfusiology
3 Bolshaya Sukharevskaya Square, Moscow, 129090
G. P. Titova
Russian Federation
Galina P. Titova, Dr. Sci. (Med.), Professor, Head of the Scientific Department of Pathological Anatomy
3 Bolshaya Sukharevskaya Square, Moscow, 129090
N. E. Kudryashova
Russian Federation
Natal'ya E. Kudryashova, Dr. Sci. (Med.), Radiologist, Chief Researcher of the Department of Radiation Diagnostics
3 Bolshaya Sukharevskaya Square, Moscow, 129090
O. V. Leshchinskaya
Russian Federation
Ol'ga V. Leshchinskaya, Dr. Sci. (Biol.), Radiologist of the Department of Radioisotope Diagnostics
3 Bolshaya Sukharevskaya Square, Moscow, 129090
R. Sh. Muslimov
Russian Federation
Rustam S. Muslimov, Cand. Sci. (Med.), Radiologist of the Department of X-ray Computed Tomography
3 Bolshaya Sukharevskaya Square, Moscow, 129090
I. N. Ponomarev
Russian Federation
Ivan N. Ponomarev, Cand. Sci. (Med.), Surgeon, Senior Researcher at the Department of Biotechnology and Transfusiology
3 Bolshaya Sukharevskaya Square, Moscow, 129090
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Supplementary files
Review
For citations:
Ofitserov A.A., Borovkova N.V., Talypov A.E., Makarov M.S., Titova G.P., Kudryashova N.E., Leshchinskaya O.V., Muslimov R.Sh., Ponomarev I.N. Cranioplasty with autograft and bone grafting material: a clinical case study. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2023;13(3):72-82. (In Russ.) https://doi.org/10.20340/vmi-rvz.2023.3.CLIN7