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Cranioplasty with autograft and bone grafting material: a clinical case study

https://doi.org/10.20340/vmi-rvz.2023.3.CLIN7

Abstract

A clinical study of the effectiveness of delayed cranioplasty with an autologous bone flap using allogenic bone grafting material was performed. The autograft was preserved, saturated with human collagen type 1, lyophilized and sterilized. Bone-plastic material was used to fill diastases. The patient was followed up in the postoperative period for 24 months. No clinical complications were registered. Radiological and radioisotope analysis showed normal fixation of the autograft after 6, 12 and 24 months. Biopsy analysis after 12 months showed the presence of regenerative processes in the absence of inflammation. The clinical result was assessed as successful.

About the Authors

A. A. Ofitserov
Sklifosovsky N.V. Research Institute of Emergency Medicine
Russian Federation

Andrey A. Ofitserov, Surgeon

3 Bolshaya Sukharevskaya Square, Moscow, 129090



N. V. Borovkova
Sklifosovsky N.V. Research Institute of Emergency Medicine
Russian Federation

Natal'ya V. Borovkova, Dr. Sci. (Med.), Head of the Scientific Department of Biotechnology and Transfusiology

3 Bolshaya Sukharevskaya Square, Moscow, 129090



A. E. Talypov
Sklifosovsky N.V. Research Institute of Emergency Medicine
Russian Federation

Aleksandr E. Talypov, Dr. Sci. (Med.), Neurosurgeon, Leading Researcher

3 Bolshaya Sukharevskaya Square, Moscow, 129090



M. S. Makarov
Sklifosovsky N.V. Research Institute of Emergency Medicine
Russian Federation

Maksim S. Makarov, Cand. Sci. (Biol.), Senior Researcher at the Department of Biotechnology and Transfusiology

3 Bolshaya Sukharevskaya Square, Moscow, 129090



G. P. Titova
Sklifosovsky N.V. Research Institute of Emergency Medicine
Russian Federation

Galina P. Titova, Dr. Sci. (Med.), Professor, Head of the Scientific Department of Pathological Anatomy

3 Bolshaya Sukharevskaya Square, Moscow, 129090



N. E. Kudryashova
Sklifosovsky N.V. Research Institute of Emergency Medicine
Russian Federation

Natal'ya E. Kudryashova, Dr. Sci. (Med.), Radiologist, Chief Researcher of the Department of Radiation Diagnostics

3 Bolshaya Sukharevskaya Square, Moscow, 129090



O. V. Leshchinskaya
Sklifosovsky N.V. Research Institute of Emergency Medicine
Russian Federation

Ol'ga V. Leshchinskaya, Dr. Sci. (Biol.), Radiologist of the Department of Radioisotope Diagnostics

3 Bolshaya Sukharevskaya Square, Moscow, 129090



R. Sh. Muslimov
Sklifosovsky N.V. Research Institute of Emergency Medicine
Russian Federation

Rustam S. Muslimov, Cand. Sci. (Med.), Radiologist of the Department of X-ray Computed Tomography

3 Bolshaya Sukharevskaya Square, Moscow, 129090



I. N. Ponomarev
Sklifosovsky N.V. Research Institute of Emergency Medicine
Russian Federation

Ivan N. Ponomarev, Cand. Sci. (Med.), Surgeon, Senior Researcher at the Department of Biotechnology and Transfusiology

3 Bolshaya Sukharevskaya Square, Moscow, 129090



References

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For citations:


Ofitserov A.A., Borovkova N.V., Talypov A.E., Makarov M.S., Titova G.P., Kudryashova N.E., Leshchinskaya O.V., Muslimov R.Sh., Ponomarev I.N. Cranioplasty with autograft and bone grafting material: a clinical case study. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2023;13(3):72-82. (In Russ.) https://doi.org/10.20340/vmi-rvz.2023.3.CLIN7

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ISSN 2226-762X (Print)
ISSN 2782-1579 (Online)