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Brain lymphoma: clinical case description

https://doi.org/10.20340/vmi-rvz.2024.5.CASE.4

Abstract

Relevance. Differential diagnosis between the brain infectious lesions and the central nervous system (СNS) oncological diseases is an urgent task in infectology.

The aim of the study is to present and analyze a primary diffuse large-cell B-cell  lymphoma  of  the  central  nervous system clinical case.

Materials and methods. The work was carried out on the basis of the clinic and the Department of Infectious Diseases with Epidemiology of SamSMU. A clinical case of primary diffuse large-cell B-cell lymphoma of the central nervous system is presented. The patient's brain CT and MRI, cerebrospinal fluid studies were performed, general clinical, biochemical, and serological diagnostic  methods were  used.

Results. The article describes a primary diffuse large-cell B-cell lymphoma of the central nervous system clinical case in a patient admitted to an infectious hospital with a directional diagnosis of unspecified etiology acute serous meningoencephalitis.

ConclusionsDifferential  diagnosis between infectious brain lesions and CNS oncological diseases manifesting with cerebral and meningeal syndromes is a difficult task for an infectious disease specialist. A comprehensive examination allows for a diagnostic search for infectious and tumor diseases of the central nervous system, to establish a final diagnosis and to develop tactics for further patient management.

About the Authors

R. B. Ohanyan
Samara State Medical University
Russian Federation

Robert B. Ohanyan, Cand. Sci. (Med.). infectious disease physician, infectious diseases department of clinics 

89, Chapaevskaya str., Samara, 443099



I. V. Roganova
Samara State Medical University
Russian Federation

Irina V. Roganova, Dr. Sci. (Med.), Docent, Professor of Department of Infectious Diseases with Epidemiology

89, Chapaevskaya str., Samara, 443099



D. Yu. Konstantinov
Samara State Medical University
Russian Federation

Dmitry Yu. Konstantinov, Dr. Sci. (Med.), Docent, Head of the Department of Infectious Diseases with Epidemiology

89, Chapaevskaya str., Samara, 443099



E. S. Kindalova
Samara State Medical University
Russian Federation

Ekaterina S. Kindalova, Cand. Sci. (Med.). Head of the infectious diseases Department of clinics

89, Chapaevskaya str., Samara, 443099



References

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3. Gubkin A.V., Zvonkov Е.E., Kremenetskaya А.M. et al. Primary central nervous system lymphomas. Clinical oncohematology. 2008;1(4):323–332. (In Russ).

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For citations:


Ohanyan R.B., Roganova I.V., Konstantinov D.Yu., Kindalova E.S. Brain lymphoma: clinical case description. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2024;14(5):101-107. (In Russ.) https://doi.org/10.20340/vmi-rvz.2024.5.CASE.4

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ISSN 2226-762X (Print)
ISSN 2782-1579 (Online)