Current trends in the treatment of complications in patients with gastric and duodenal ulcer disease (review of foreign literature)
https://doi.org/10.20340/vmi-rvz.2024.6.CLIN.3
Abstract
Relevance. Peptic ulcer disease is a common disease that occurs in 5–10 % of the world population. Despite the sharp decrease in morbidity and hospitalization rates of patients with peptic ulcer disease of the stomach and duodenum, for the last 30 years lethality in such patients remains at a high level, and complications occur with a frequency of 10–20 %.
Purpose: to present the literature review of foreign researchers devoted to the modern trends of complications treatment in patients with peptic ulcer and duodenal ulcer disease.
Material and methods. Literature sources in English on this topic in PubMed, MEDUNE, Google Scholar databases were analyzed. The review highlights clinical studies devoted to the treatment of complications of gastric and duodenal ulcer disease: ulcer bleeding, perforative ulcer, and pyloroduodenal stenosis.
Conclusion. Complications of gastric and duodenal ulcer disease remain complex therapeutic and surgical problems. Despite the achieved successes, the results of treatment of complications remain unsatisfactory, which requires further study and search for their improvement.
About the Authors
V. I. Belokonev
Samara State Medical University
Russian Federation
Competing Interests:
Russian Federation
Vladimir I. Belokonev, Dr. Sci. (Med.), Honored Doctor of the Russian Federation, Professor of the Department of Surgical Diseases of Children and Adults
89, Chapaevskaya, Samara, 443099
Competing Interests:
The authors declare no conflict of interest.
S. Yu. Pushkin
Samara State Medical University
Russian Federation
Competing Interests:
Russian Federation
Sergey Yu. Pushkin, Dr. Sci. (Med.), Docent, Head of the Department of Surgical Diseases of Children and Adults; Chief Physician
89, Chapaevskaya, Samara, 443099
Competing Interests:
The authors declare no conflict of interest.
K. P. Yadav
Samara State Medical University
Russian Federation
Competing Interests:
Russian Federation
Krishn Pratap Yadav, Applicant, Department of Surgical Diseases of Children and Adults
89, Chapaevskaya, Samara, 443099
Competing Interests:
The authors declare no conflict of interest.
A. A. Serov
Samara State Medical University
Russian Federation
Competing Interests:
Russian Federation
Aleksandr A. Serov, 3rd year student of the Institute of Clinical Medicine
89, Chapaevskaya, Samara, 443099
Competing Interests:
The authors declare no conflict of interest.
References
1. Lau J.Y., Sung J., Hill C. et al. Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion. 2011;84(2):102-113.
2. Chukwuneke F.N., Ezeonu C.T., Onyire B.N., Ezeonu P.O. Culture and biomedical care in Africa: the influence of culture on biomedical care in a traditional African society, Nigeria, West Africa. Nigerian Journal of Medicine. 2012;21(3):331-333.
3. Ramakrishnan K., Salinas R.C. Peptic ulcer disease. American Family Physician. 2007;76(7):1005-1012.
4. Chalya P.L. Clinical profile and outcome of surgical treatment of perforated peptic ulcers in Northwestern Tanzania: A tertiary hospital experience. World J Emerg Surg. 2011;6:31. https://doi.org/10.1186/1749-7922-6-31
5. Dakubo J.C.B. Gastroduodenal peptic ulcer perforation. East African Medical Journal. 2009;86(3):100-109.
6. Sondashi K.J., Odimba B.F.K., Kelly P. A Cross-sectional Study on Factors Associated With Perforated Peptic Ulcer Disease in Adults Presenting to UTH, Lusaka. Medical journal of Zambia. 2011;38(2):15-22. https://doi.org/10.4314/MJZ.V38I2
7. Buck D.L., Vester-Andersen M., Møller M.H. Accuracy of clinical prediction rules in peptic ulcer perforation: an observational study. Scand J Gastroenterol. 2012 Jan;47(1):28-35. https://doi.org/10.3109/00365521.2011.639078
8. Saverio S. Di. Diagnosis and treatment of perforated or bleeding peptic ulcers: 2013 WSES position paper. World Journal of Emergency Surgery. 2014; 9(45).
9. Zittel T.T. Surgicalmanagement of peptic ulcer disease today – indication, technique and outcome. Langenbeck’s Archives of Surgery. 2000;385(2):84-96.
10. Søreide K. Perforated peptic ulcer. Lancet. 2015;386(10000):1288-1298.
11. Gona S.K., Postoperative Morbidity and Mortality of Perforated Peptic Ulcer: Retrospective Cohort Study of Risk Factors among Black Africans in Côte d'Ivoire. Gastroenterol Res Pract. 2016;2016:2640730. https://doi.org/10.1155/2016/2640730
12. Wilhelmsen M. Surgical complications after open and laparoscopic surgery for perforated peptic ulcer in a nationwide cohort. Br J Surg. 2015;102(4):382-387. https://doi.org/10.1002/bjs.9753
13. Jairath V., Kahan B.C., Logan R.F. et al. National audit of the use of surgery and radiological embolization after failed endoscopic haemostasis for nonvariceal upper gastrointestinal bleeding. Br J Surg. 2012;99(12):1672-80. https://doi.org/10.1002/bjs.8932
14. Thorsen K. Trends in diagnosis and surgical management of patients with perforated peptic ulcer. J Gastrointest Surg. 2011 Aug; 15(8):1329-35. https://doi.org/10.1007/s11605-011-1482-1
15. Laursen S.B. Rebleeding in peptic ulcer bleeding – a nationwide cohort study of 19,537 patients. Scand J Gastroenterol. 2022;57(12):1423-1429. https://doi.org/10.1080/00365521.2022.2098050
16. Millat B. Emergency surgical treatment for bleeding duodenal ulcer: oversewing plus vagotomy versus gastric resection, a controlled randomized trial. French Associations for Surgical Research. World J Surg. 1993;17(5):568-574. https://doi.org/10.1007/BF01659109
17. Kyaw M., Tse Y., Ang D., Ang T.L., Lau J. Embolization versus surgery for peptic ulcer bleeding after failed endoscopic hemostasis: a metaanalysis. Endosc Int Open. 2014 Mar;2(1):E6-E14. https://doi.org/10.1055/s-0034-1365235
18. Nikishenko A.A. Dekompensirovannyĭ piloroduodenal'nyĭ stenoz, obuslovlennyĭ solitarnoĭ kistoĭ stenki zheludka [Decompensated pyloroduodenal stenosis caused by a solitary cyst of the stomach wall]. Vrach Delo. 1991;3:104-106.
19. Fadil A. Les sténoses pyloro-duodénales d'origine ulcéreuse. A propos de 260 cas [Pyloroduodenal stenosis of ulcer origin. Apropos of 260 cases]. J Chir (Paris). 1992;129(1):27-30.
20. Camacho C. Management of gastrojejunostomy leakage after emergency gastrectomy. International Surgery Journal. 2021;8(1):357-361. https://doi.org/10.18203/2349-2902.isj20205424
21. Cheng M., Li W.H., Cheung M.T. Early outcome after emergency gastrectomy for complicated peptic ulcer disease. Hong Kong Med J. 2012;18(4):291-8.
22. Tanaka R., Kosugi S.I., Sakamoto K., Yajima K., Ishikawa T., Kanda T. et al. Treatment for perforated gastric ulcer: a multi-institutional retrospective review. J Gastrointest Surg. 2013;17(12):2074-81.
23. Schots JPM, Luyer MDP, Nieuwenhuijzen GAP. Abdominal Drainage and Amylase Measurement for Detection of Leakage After Gastrectomy for Gastric Cancer. J Gastrointest Surg. 2018; 22(7):1163-70.
24. Tan KK, Quek TJ, Wong N, Li KK, Lim KH. Early outcome following emergency gastrectomy. Ann Acad Med Singap. 2012; 41(10):451-6.
25. Lee HL, Cho JY, Cho JH, Park JJ, Kim CG, Kim SH, et al. Efficacy of the Over-the-Scope Clip System for Treatment of Gastrointestinal Fistulas, Leaks, and Perforations: A Korean Multi-Center Study. Clin Endosc. 2018;51(1):61-5.
26. Schmidt F, Mennigen R, Vowinkel T, Neumann PA, Senninger N, Palmes D, et al. Endoscopic Vacuum Therapy (EVT)-a New Concept for Complication Management in Bariatric Surgery. Obes Surg. 2017; 27(9):2499-505.
27. Chalkoo, Mushtaq. A Short Term Outcome of Laparoscopic Hand Sewn and Stapled Gastrojejunostomy in Gastric Outlet Obstruction – An Observational Study. International Journal of Surgery & Surgical Techniques. 2018;2. https://doi.org/10.23880/IJSST-16000118
28. Abdel-Salam WN, Katri KM, Bessa SS, El-Kayal el-SA. Laparoscopic-assisted truncal vagotomy and gastro-jejunostomy: trial of simplification. J Laparoendosc Adv Surg Tech A. 2009; 19(2):125-7. https://doi.org/10.1089/lap.2008.0250
29. Siu WT, Tang CN, Law BK, Chau CH, Yau KK, Yang GP, Li MK. Vagotomy and gastrojejunostomy for benign gastric outlet obstruction. J Laparoendosc Adv Surg Tech A. 2004 Oct; 14(5):266-9. https://doi.org/10.1089/lap.2004.14.266
30. Choi YB. Laparoscopic gatrojejunostomy for palliation of gastric outlet obstruction in unresectable gastric cancer. Surg Endosc. 2002 Nov;16(11):1620-6. https://doi.org/10.1007/s00464-002-0010-5
31. Jaka H., Mchembe M.D., Rambau P.F. et al. Gastric outlet obstruction at Bugando Medical Centre in Northwestern Tanzania: a prospective review of 184 cases. BMC Surg. 2013;13(41). https://doi.org/10.1186/1471-2482-13-41
32. Gonzalez R, Lin E, Venkatesh KR, Bowers SP, Smith CD. Gastrojejunostomy during laparoscopic gastric bypass: analysis of 3 techniques. Arch Surg. 2003 Feb;138(2):181-4. https://doi.org/10.1001/archsurg.138.2.181
33. Gralnek IM, Dumonceau JM, Kuipers EJ, et al. Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2015;47(10):a1-a46. https://doi.org/10.1055/s-0034-1393172
34. Blatchford Oliver et al. Acute upper gastrointestinal haemorrhage in west of Scotland: case ascertainment study. BMJ. 1997;315510:514.
35. Hearnshaw SA, Logan RF, Palmer KR, Card TR, Travis SP, Murphy MF. Outcomes following early red blood cell transfusion in acute upper gastrointestinal bleeding. Aliment Pharmacol Ther. 2010 Jul; 32(2):215-24. https://doi.org/10.1111/j.1365-2036.2010.04348.x
36. Leerdam van M.E., Tytgat G.N.J. Acute gastrointestinal bleeding. Best practice & research. Clinical gastroenterology. 2008;22(2):207-8 .
37. Dunne PDJ, Laursen SB, Laine L, Dalton HR, Ngu JH, Schultz M. et al. Previous Use of Antithrombotic Agents Reduces Mortality and Length of Hospital Stay in Patients With High-risk Upper Gastrointestinal Bleeding. Clin Gastroenterol Hepatol. 2019 Feb;17(3):440-447.e2. https://doi.org/10.1016/j.cgh.2018.04.046
38. Götz M, Anders M, Biecker E, et al. S2k-Leitlinie Gastrointestinale Blutung [S2k Guideline Gastrointestinal Bleeding – Guideline of the German Society of Gastroenterology DGVS]. Z Gastroenterol. 2017;55(9):883-936. https://doi.org/10.1055/s-0043-116856
39. Sostres C, Carrera-Lasfuentes P, Benito R, et al. Peptic ulcer bleeding risk. The role of Helicobacter pylori infection in NSAID/low-dose aspirin users. Am J Gastroenterol. 2015;110(5):684-689.
40. Pérez-Aisa MA, Del Pino D, Siles M, Lanas A. Clinical trends in ulcer diagnosis in a population with high prevalence of Helicobacter pylori infection. Aliment Pharmacol Ther. 2005 Jan 1;21(1):65-72. https://doi.org/10.1111/j.1365-2036.2004.02297.x
41. Sung JJ, Kuipers EJ, El-Serag HB. Systematic review: the global incidence and prevalence of peptic ulcer disease. Aliment Pharmacol Ther. 2009; 29(9):938-946.
42. Knuuti J, Wijns W, Saraste A, et al. 2019 ESC guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J. 2020; 41(3):407-477.
43. Sarri GL, Grigg SE, Yeomans ND. Helicobacter pylori and low-dose aspirin ulcer risk: A meta-analysis. J Gastroenterol Hepatol. 2019 Mar;34(3):517-525. https://doi.org/10.1111/jgh.14539
44. Lanas A, Garcia-Rodriguez LA, Arroyo MT, et al. Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and combinations. Gut. 2006;55(12):1731-1738.
45. Zeitoun JD, Rosa-Hezode I, Chryssostalis A, et al. Epidemiology and adherence to guidelines on the management of bleeding peptic ulcer: a prospective multicenter observational study in 1140 patients. Clin Res Hepatol Gastroenterol. 2012;36(3):227-234.
46. Gisbert JP et al. Long-term follow-up of 1,000 patients cured of Helicobacter pylori infection following an episode of peptic ulcer bleeding. The American journal of gastroenterology. 2012;107(8):1197-204. https://doi.org/10.1038/ajg.2012.132
47. Sverdén E, Brusselaers N, Wahlin K, Lagergren J. Time latencies of Helicobacter pylori eradication after peptic ulcer and risk of recurrent ulcer, ulcer adverse events, and gastric cancer: a population-based cohort study. Gastrointest Endosc. 2018 Aug;88(2):242-250.e1. https://doi.org/10.1016/j.gie.2017.11.035
48. Malfertheiner P, Megraud F, Rokkas T, Gisbert JP, Liou JM, Schulz C, et al. European Helicobacter and Microbiota Study group. Management of Helicobacter pylori infection: the Maastricht VI/Florence consensus report. Gut. 2022 Aug 8: gutjnl-2022-327745. https://doi.org/10.1136/gutjnl-2022-327745
49. Larssen L, Moger T, Bjørnbeth BA, Lygren I, Kløw NE. Transcatheter arterial embolization in the management of bleeding duodenal ulcers: a 5.5-year retrospective study of treatment and outcome. Scand J Gastroenterol. 2008;43(2):217-22. https://doi.org/10.1080/00365520701676443
50. Quan S, Frolkis A, Milne K, Molodecky N, Yang H, Dixon E, Ball CG, Myers RP, Ghosh S, Hilsden R, van Zanten SV, Kaplan GG. Uppergastrointestinal bleeding secondary to peptic ulcer disease: incidence and outcomes. World J Gastroenterol. 2014 Dec 14;20(46):17568-77. https://doi.org/10.3748/wjg.v20.i46.17568
51. Rockall T.A., Logan R.F., Devlin H.B., Northfield T.C. Risk Assessment after Acute Upper Gastrointestinal Haemorrhage. Gut. 1996;38:316-321. http://dx.doi.org/10.1136/gut.38.3.316
52. Lin HJ, Lo WC, Cheng YC, Perng CL. Effects of 3-day IV pantoprazole versus omeprazole on 24-hour intragastric acidity at 3 days in Chinese patients with duodenal ulcer: A single-center, prospective, randomized, comparative, pilot trial. Clin Ther. 2006 Sep;28(9):1303-7. https://doi.org/10.1016/j.clinthera.2006.09.001
53. Forrest JA, Finlayson ND, Shearman DJ. Endoscopy in gastrointestinal bleeding. Lancet. 1974 Aug 17;2(7877):394-7. https://doi.org/10.1016/s0140-6736(74)91770-x. PMID: 4136718.
54. Tarasconi A, Coccolini F, Biffl WL, Tomasoni M, Ansaloni L, Picetti E, et al. Perforated and bleeding peptic ulcer: WSES guidelines. World J Emerg Surg. 2020 Jan 7;15:3. https://doi.org/10.1186/s13017-019-0283-9
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For citations:
Belokonev V.I., Pushkin S.Yu., Yadav K.P., Serov A.A. Current trends in the treatment of complications in patients with gastric and duodenal ulcer disease (review of foreign literature). Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2024;14(6):67-72. (In Russ.) https://doi.org/10.20340/vmi-rvz.2024.6.CLIN.3
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