Epidemiology of dyslipidemia in post-kidney transplant patients: a multicenter retrospective cohort study (EDIS-PTP 2025). Rationale and study design

Background. Dyslipidemia is a major risk factor for cardiovascular events after kidney transplantation. Insufficient data are available in the Russian literature on the prevalence of dyslipidemia in kidney transplant patients and the effectiveness of lipid-lowering therapy regimens.

Study objective: to determine the incidence of dyslipidemia in kidney transplant patients, the frequency of lipid-lowering therapy, and its effectiveness.

Subject and methods. This multicenter retrospective cohort study included four sequential stages: Stages I and II – selection of kidney transplant patients based on inclusion and exclusion criteria; Stages III and IV – identification of a group of patients with and without dyslipidemia from the total number of patients included in the study. During Phase IV, the following will be performed: demographic and general clinical characteristics of patients, characterization based on the presence of risk factors for cardiovascular events; identification of patients on and without lipid-lowering therapy; patients with the following lipid metabolism parameters: LDL-C ≥1.4 mmol/L and TG ≥1.7 mmol/L; LDL-C <1.4 mmol/L and TG <1.7 mmol/L; LDL-C ≥1.4 mmol/L and TG <1.7 mmol/L; and LDL-C <1.4 mmol/L and TG ≥1.7 mmol/L; analysis of the frequency of prescription of lipid-lowering therapy and its effectiveness. 

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