Preview

Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)

Advanced search

The problem of verification of malignant neoplasms of the stomach in surgical practice

https://doi.org/10.20340/vmi-rvz.2022.5.CLIN

Abstract

Relevance. Despite numerous efforts made in recent decades, the arsenal of cancer diagnostics is still significantly limited. The purpose of study: to analyze the problem of differential diagnosis of early stage stomach cancer and non-oncological diseases of the abdominal cavity. Materials and methods. In the course of the work, current literary sources of domestic and foreign authors on a given topic were analyzed. Results. The early stages of malignant neoplasms of the stomach are usually asymptomatic or accompanied by nonspecific signs, such as dyspepsia. Symptoms of the development of malignant tumors of the stomach at an early stage may be indistinguishable from the symptoms of benign dyspepsia, while the presence of established "alarming" symptoms may mean a progressive inoperable disease. However, the evidence supporting the use of "alarming" symptoms as selection criteria for endoscopy still remains contradictory, since the presence of "alarming" symptoms in the clinical picture is not always associated with the detection of malignant neoplasms, it is also worth noting that the overall prevalence of these symptoms in the population of patients suffering from dyspeptic disorders is high, while while the number of patients with a history of gastrointestinal cancer is relatively low. Conclusion. Despite the observed trend of decreasing morbidity and mortality, malignant neoplasms of the stomach remain an important part in the structure of oncological diseases. Many of the risk factors remain insufficiently studied and should be the subject of further research to achieve more specific, targeted preventive measures.

About the Authors

D. A. Maksimov
Tver State Medical University
Russian Federation

Tver.


Competing Interests:

The authors declare no competing interests.



A. N. Sergeev
Tver State Medical University
Russian Federation

Tver.


Competing Interests:

The authors declare no competing interests.



A. M. Morozov
Tver State Medical University
Russian Federation

Tver.


Competing Interests:

The authors declare no competing interests.



M. A. Belyak
Tver State Medical University
Russian Federation

Tver.


Competing Interests:

The authors declare no competing interests.



E. N. Nozhenko
Tver State Medical University
Russian Federation

Tver.


Competing Interests:

The authors declare no competing interests.



References

1. Sung H., Ferlay J., Siegel R.L., Laversanne M., Soerjomataram I., Jemal A., Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209-249.

2. Ilic M., Ilic I. Epidemiology of stomach cancer. World J Gastroenterol. 2022;28(12):1187-1203. https://doi.org/10.3748/wjg.v28.i12.1187

3. Bray F., Ferlay J., Soerjomataram I., Siegel R.L., Torre L.A., Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394-424.

4. Kosarev E.I., Nesterov S.N., Khanaliev B.V. The use of cancer markers in urological practice: PSA as the most frequently used marker in differential diagnosis in oncourologists. Bulletin of the National Medical and Surgical Center named after N.I. Pirogov. 2018;4:143-146. (In Russ). https://doi.org/10.25881/BPNMSC.2018.52.12.028

5. Akhmetzhanov O.T. Colorectal cancer (literature review). Bulletin of the Kyrgyz-Russian Sla vic University. 2017;10:16-20. (In Russ).

6. Eremina E.Y. The value of serum cancer markers in the diagnosis of malignant tumors of the digestive system. Medical alphabet. 2013;2:32-37. (In Russ).

7. Amlaev K.R., Dakhkilgova H.T. Literacy in health issues: concept, classification, assessment methods, improvement measures (scientific review). Preventive and clinical medicine. 2018;4(69):21-26. (In Russ).

8. Ushkalova E.A., Zyryanov S.K., Gopienko I.A. Economic problems of pharmacotherapy of oncological diseases. Pharmacoeconomics. Modern pharmacoeconomics and pharmacoepidemiology. 2020;1:64-70. (In Russ). https://doi.org/10.17749/2070-4909.2020.13.1.64-70

9. Abakarova E.G., Khurtsev K.V. Features of psychoemotional stability of cancer patients at different stages of treatment. Psychiatry, psychotherapy and clinical psychology. 2020;4:708-715. (In Russ). https://doi.org/10.34883/PI.2020.11.4.004

10. Tobore T.O. On the need for the development of a cancer early detection, diagnostic, prognosis, and treatment response system. Future Sci OA. 2019;6(2):FSO439. https://doi.org/10.2144/fsoa-2019-0028

11. Holtedahl K. Challenges in early diagnosis of cancer: the fast track. Scand J Prim Health Care. 2020;38(3):251-252. https://doi.org/10.1080/02813432.2020.1794415

12. Zhou Y., Mendonca S.C., Abel G.A., et al. Variation in ‘fast-track' referrals for suspected cancer by patient characteristic and cancer diagnosis: evidence from 670 000 patients with cancers of 35 different sites. Br J Cancer. 2018;118(1):24—31.

13. Scheel B.I., Holtedahl K. Symptoms, signs, and tests: the general practitioner's comprehensive approach towards a cancer diagnosis. Scand J Prim Health Care. 2015;33(3):170-177.

14. Solvang M., Elnegaard S., Jarbol D.E. Urological symptoms among 23,240 men in the general Danish population - concerns about symptoms, their persistence and influence on primary care contacts. Scand J Prim Health Care. 2018;36(3):227-236.

15. Cormedi M.C.V., Katayama M.L.H., Guindalini R.S.C., Faraj S.F., Folgueira MAAK. Survival and prognosis of young adults with gastric cancer. Clinics (Sao Paulo). 2018;73(suppl 1):e651s. https://doi.org/10.6061/clinics/2018/e651s

16. Pasechnikov V., Chukov S., Fedorov E., Kikuste I., Leja M. Gastric cancer: prevention, screening and early diagnosis. World J Gastroenterol. 2014;20(38):13842-62. https://doi.org/10.3748/wjg.v20.i38.13842

17. Sorokovikova T.V., Morozov A.M., Zhukov S.V. The role of non-invasive research methods in modern clinical practice. Modern problems of science and education. 2022;2:137. (In Russ). https://doi.org/10.17513/spno.31502

18. Sergeev A.N., Morozov A.M., Charyev Yu.O., Belyak M.A., Ryzhova T.S., Morozova A.D., Horak K.I., Belyak M.A. On the possibility of using medical thermography in clinical practice. Preventive medicine. 2022;4:82-88. (In Russ). https://doi.org/10.17116/profmed20222504182

19. Correa P. Gastric cancer: overview. Gastroenterol Clin North Am. 2013;42(2):211-7. https://doi.org/10.1016/j.gtc.2013.01.002

20. Zemlyanoi V.P., Sigua B.V., Gudkov I.I. et al. Diagnosis and treatment of stomach cancer complicated by bleeding. Bulletin of the I.I. Mechnikov Northwestern State Medical University. 2017;1:15-20. (In Russ)].

21. 21 Елманов И.Е., Плеханов А.А., Климов А.В. Рак желудка. NovaInfo.Ru. 2021;126:120-122. [Elmanov I. E., Plekhanov A.A., Klimov A.V. Stomach cancer. NovaInfo.Ru. 2021;126:120-122. (In Russ).

22. Moala AlHazmi R., Nasrallah Alfaraj D., Nasser AlNaimi S., Mohammed AlQahtani S., Hamed AlJuwayed M., Mohammed Zakriea H., Foula M.S. A Rare Presentation of Gastric Carcinoma With Gastric Perforation and Septic Shock. Cureus. 2021;13(10):e18657. https://doi.org/10.7759/cureus.18657

23. Wanebo H.J., Kennedy B.J., Chmiel J., Steele G., Winchester D., Osteen R. Cancer of the stomach. A patient care study by the American College of Surgeons. Ann Surg. 1993;218(5):583-92.

24. Olokoba A.B., Obateru O.A., Bojuwoye M.O., Ibrahim O.K., Olokoba L.B. That dyspepsia in the young could be cancer. Niger Med J. 2013;54(2):143-5. https://doi.org/10.4103/0300-1652.110053

25. Mbiine R., Nakanwagi C., Kituuka O. High rates of gastroesophageal cancers in patients with dyspepsia undergoing upper gastrointestinal endoscopy in Uganda. Endosc Int Open. 2021;9(7):E997-E1000. https://doi.org/10.1055/a-1480-7231

26. Rahman M.M., Ghoshal U.C., Kibria M.G., Sultana N., Yusuf M.A., Nahar S., Ahmed F., Rowshon A., Hasan M. Functional Dyspepsia, Peptic Ulcer, and Helicobacter pylori Infection in a Rural Community of South Asia: An Endoscopy-Assisted Household Survey. Clin Transl Gastroenterol. 2021;12(4):e00334. https://doi.org/10.14309/ctg.0000000000000334

27. Assefa B., Tadesse A., Abay Z., Abebe A., Tesfaye T., Tadesse M., Molla A. Peptic ulcer disease among dyspeptic patients at endoscopy unit, University of Gondar hospital, Northwest Ethiopia. BMC Gastroenterol. 2022;22(1):164. https://doi.org/10.1186/s12876-022-02245-6

28. Sheptulin A.A., Rabodyagova Yu.S. Combination of functional dyspepsia and gastroesophageal reflux disease: controversial and unresolved issues. Crimean Therapeutic Journal. 2020;2:12-16. (In Russ).

29. Ghoshal U.C., Singh R., Chang F.Y. et al. Epidemiology of uninvestigated and functional dyspepsia in Asia: Facts and fiction. J Neu-rogastroenterol Motil. 2011;17(3):235-44.

30. Manes G., Balzano A., Marone P., Lioniello M., Mosca S. Appropriateness and diagnostic yield of upper gastrointestinal endoscopy in an open-access endoscopy system: a prospective observational study based on the Maastricht guidelines. Aliment Pharmacol Ther. 2002;16:105-110.

31. Harmon R.C., Peura D.A. Evaluation and management of dyspepsia. Therap Adv Gastroenterol. 2010;3(2):87-98. https://doi.org/10.1177/1756283X09356590

32. Black C.J., Houghton L.A., Ford A.C. Insights into the evaluation and management of dyspepsia: recent developments and new guidelines. Therap Adv Gastroenterol. 2018;11:1756284818805597. https://doi.org/10.1177/1756284818805597

33. Odeghe E.A., Adeniyi O.F., Oyeleke G.K., Keshinro S.O. Use of alarm features in predicting significant endoscopic findings in Nigerian patients with dyspepsia. Pan Afr Med J. 2019;34:66. https://doi.org/10.11604/pamj.2019.34.66.18848

34. Oustamanolakis P., Tack J. Dyspepsia: organic versus functional. J Clin Gastroenterol. 2012;46:175-190. https://doi.org/ 10.1097/MCG.0b013e318241b335

35. Shetty A., Balaraju G., Shetty S., Pai C.G. Diagnostic utility of alarm features in predicting malignancy in patients with dyspeptic symptoms. Indian J Gastroenterol. 2021;40(2):183-188. https://doi.org/10.1007/s12664-021-01155-x

36. Fransen G.A., Janssen M.J., Muris J.W., Laheij R.J., Jansen J.B. Meta-analysis: the diagnostic value of alarm symptoms for upper gastrointestinal malignancy. Aliment Pharmacol Ther. 2004;20:1045-1052.

37. Sundar N., Muraleedharan V., Pandit J., Green J.T., Crimmins R., Swift G.L. Does endoscopy diagnose early gastrointestinal cancer in patients with uncomplicated dyspepsia? Postgrad Med J. 2006;82:52-54.

38. Meineche-Schmidt V., Jorgensen T. ‘Alarm symptoms' in patients with dyspepsia: a three-year prospective study from general practice. Scand J Gastroenterol. 2002;37:999-1007.

39. Lieberman D., Fennerty M.B., Morris C.D., Holub J., Eisen G., Sonnenberg A. Endoscopic evaluation of patients with dyspepsia: results from the national endoscopic data repository. Gastroenterology. 2004;127:1067-1075.

40. Maconi G., Manes G., Porro G.B. Role of symptoms in diagnosis and outcome of gastric cancer. World J Gastroenterol. 2008;14(8):1149-55. https://doi.org/10.3748/wjg.14.1149

41. Kapoor N., Bassi A., Sturgess R., Bodger K. Predictive value of alarm features in a rapid access upper gastrointestinal cancer service. Gut. 2005;54:40-45.

42. Tsukanov V.V., Vasyutin A.V., Tonkikh Yu.L. Modern aspects of stomach cancer prevention. 2020;7:37-40. (In Russ). https://doi.org/10.31550/1727-2378-2020-19-7-37-40

43. Yada T., Yokoi C., Uemura N. The current state of diagnosis and treatment for early gastric cancer. Diagn Ther Endosc. 2013;2013:241320. https://doi.org/10.1155/2013/241320

44. Humphrys E., Walter F.M., Rubin G., Emery J.D., Johnson M., Richards A., Fitzgerald R.C., Viswanath Y.K., Burt J. Patient symptom experience prior to a diagnosis of oesophageal or gastric cancer: a multi-methods study. BJGP Open. 2020;4(1):bjgpopen20X101001. https://doi.org/10.3399/bjgpopen20X101001

45. Suh Y.S., Lee J., Woo H., Shin D., Kong S.H., Lee H.J., Shin A., Yang H.K. National cancer screening program for gastric cancer in Korea: Nationwide treatment benefit and cost. Cancer. 2020;126(9):1929-1939. https://doi.org/10.1002/cncr.32753

46. Azimkhanova G. K., Ibragimova S.I. The incidence of stomach cancer among men. Theoretical & Applied Science. 2017;12(56):205-208. (In Russ) https://doi.org/10.15863/TAS.2017.12.56.32


Review

For citations:


Maksimov D.A., Sergeev A.N., Morozov A.M., Belyak M.A., Nozhenko E.N. The problem of verification of malignant neoplasms of the stomach in surgical practice. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2022;(5):50-57. (In Russ.) https://doi.org/10.20340/vmi-rvz.2022.5.CLIN

Views: 264


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2226-762X (Print)
ISSN 2782-1579 (Online)