Treatment of periprosthetic knee joint infection using a spacer with a mixed carbonsilver antibacterial coating in the medium term
https://doi.org/10.20340/vmi-rvz.2024.1.CLIN.1
Abstract
Relevance. Total endoprosthetics is a one of the most common operation for knee pathology. A major complication of joint replacement surgery is periprosthetic infection (PPI). In this work, we looked at the mid-term clinical outcomes of using spacers coated with linear chain carbon doped with silver ions (LC-Ag+) to treat PJI.
Object and methods. The mid-term clinical results of 31 patients with LUP-Ag+ coated spacers were compared to 31 control patients groups utilizing tests of the functional and clinical scales KSS, visual analogue pain scale (VAS), EQVAS, and EQ-5D-5L 2 years following surgery.
Results. According to the clinical questionnaire, the LC-Ag+ group's mid-term outcomes were statistically better than the control group's for clinical KSS 90 vs. 69 points (p = 0.002) and functional KSS – 75.5 vs. 65 points (p = 0.005), VAS – 1.6 vs. 4.2 points (p < 0.001), EQVAS – 95 vs. 72.5 points (p < 0.001), EQ-5D-5L – 0.84 vs. 0.59 points (p = 0.008), respectively.
Conclusions. The combination LC-Ag+ coating increases the mid-term effects of PPI treatment.
About the Authors
L. I. Malyuchenko
Federal Center of Traumatology, Orthopedics and Endoprosthetics
Russian Federation
Russian Federation
Leonid I. Malyuchenko - Traumatologist-orthopedist,
33, Fedora Gladkova str., Cheboksary, 428020
N. S. Nikolaev
Federal Center of Traumatology, Orthopedics and Endoprosthetics;
I.N. Ulyanov Chuvash State University
Russian Federation
Russian Federation
Nikolay S. Nikolaev - Dr. Sci. (Med.), Professor, Chief Physician, 33, Fedora Gladkova str., Cheboksary, 428020;
Head of the Department of Traumatology, Orthopedics and Extreme Medicine, 15, Moskovsky Ave., Cheboksary, 428015
V. Yu. Emel'yanov
Federal Center of Traumatology, Orthopedics and Endoprosthetics;
I.N. Ulyanov Chuvash State University
Russian Federation
Russian Federation
Vladimir U. Emelianov - Cand. Sci. (Med.), methodologist, 33, Fedora Gladkova str., Cheboksary, 428020;
Associate Professor of the Department of Pharmacology, Clinical Pharmacology and Biochemistry, 15, Moskovsky Ave., Cheboksary, 428015
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Review
For citations:
Malyuchenko L.I., Nikolaev N.S., Emel'yanov V.Yu. Treatment of periprosthetic knee joint infection using a spacer with a mixed carbonsilver antibacterial coating in the medium term. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2024;14(1):47-54. (In Russ.) https://doi.org/10.20340/vmi-rvz.2024.1.CLIN.1
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