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Current approaches to surgical treatment of soft tissue defects using tissue expansion techniques

https://doi.org/10.20340/vmi-rvz.2025.5.CLIN.6

Abstract

Background. The problem of closing extensive wound defects remains a challenging task in modern surgery. The increasing number of technogenic disasters, road traffic accidents, military operations, and terrorist attacks leads to a rise in patients with extensive soft tissue defects that cannot be managed using conventional suturing techniques.

Objective. To analyze the current state of the problem of wound defect closure using acute and gradual tissue stretching methods based on domestic and international literature data.

Materials and methods. An analysis of scientific publications on tissue distraction methods from PubMed, eLibrary, and CyberLeninka databases was conducted. The design features and clinical effectiveness of modern devices for exogenous tissue stretching were reviewed.

Results. A classification of wound adaptation-repositioning devices (WARD) is presented, divided into five subgroups: needle-type, suture-type, wire-type, rod-type, and adhesive-type. The principles of operation of intratissue devices (expanders) and extratissue devices are described. The advantages and limitations of each method, as well as indications and contraindications for their use, are analyzed. Current trends in device improvement, including automated tension control and mathematical justification of distraction parameters, are highlighted.

Conclusion. The method of gradual tissue distraction is a promising approach for treating patients with extensive wound defects, contributing to reduced hospitalization duration and treatment costs. Further development of new devices and algorithms adapted to individual wound defect characteristics is required.

About the Authors

M. Yu. Kabanov
Hospital for war veterans; North-Western State Medical University named after. I.I. Mechnikova
Россия

Maksim Yu. Kabanov, Dr. Sci. (Med.), Head of the Hospital, Narodnaya st., 21, bldg. 2, St. Petersburg, 193079;

Professor, Department of General Surgery, Piskarevsky pr., 47, St. Petersburg, 195067



N. I. Glushkov
North-Western State Medical University named after. I.I. Mechnikova; Hospital for war veterans
Россия

Nikolay I. Glushkov, Dr. Sci. (Med.), Professor, Head of the Department of General Surgery, 

Piskarevsky pr., 47, St. Petersburg, 195067;

Narodnaya st., 21, bldg. 2, St. Petersburg, 193079



V. O. Miroshnichenko
Hospital for war veterans
Россия

Vyacheslav O. Miroshnichenko, Surgeon, Purulent Surgery Department,

Narodnaya st., 21, bldg. 2, St. Petersburg, 193079



T. L. Gorshenin
Hospital for war veterans; North-Western State Medical University named after. I.I. Mechnikova
Россия

Timofey L. Gorshenin, Dr. Sci. (Med.), Deputy Head of the Hospital for Surgery, Narodnaya st., 21, bldg. 2, St. Petersburg, 193079;

Associate Professor, Department of General Surgery, Piskarevsky pr., 47, St. Petersburg, 195067



M. A. Binienko
Hospital for war veterans
Россия

Mikhail A. Binienko, Cand. Sci. (Med.), Head of Purulent Surgery Department No. 6, 

Narodnaya st., 21, bldg. 2, St. Petersburg, 193079



S. G. Izmaylov
City Clinical Hospital No. 7 named after. E.L. Berezova
Россия

Sergey G. Izmaylov, Dr. Sci. (Med.), Professor, Consulting Professor,

st. October Revolution, 66a, Nizhny Novgorod, 603011



S. N. Bogdanov
City Clinical Hospital No. 7 named after. E.L. Berezova
Россия

Sergey N. Bogdanov, Cand. Sci. (Med.), Surgeon, 

st. October Revolution, 66a, Nizhny Novgorod, 603011



References

1. Parkhomchuk D.S. Organization of medical evacuation measures in the context of a local armed conflict. Disaster Medicine. 2018;4(104):14-17. (In Russ.)

2. Dubinkin VA, Khaliman AS. The problem of terrorism and medical care for victims (scientific review). In the world of scientific discoveries. 2018;10(4):258-272. (In Russ.)

3. Mitish VA, Amiroslanov YuL. Plastic and reconstructive operations in purulent surgery and traumatology. Surgery. 2000;4:41-44. (In Russ.)

4. Verhaegen PD, Schouten HJ, Tigchelaar-Gutter W, et al. Adaptation of the dermal collagen structure of human skin and scar tissue in response to stretch: an experimental study. Wound Repair Regen. 2012;20(5):658-666.

5. Beschatnov VV, Orlinskaya NYu, Kudykin MN. Experimental and clinical justification for the use of dosed dermotension in the first phase of the wound process. Surgical News. 2012;2. (In Russ.) URL: https://cyberleninka.ru/article/n/eksperimentalno-klinicheskoeobosnovanie-primeneniya-dozirovannoy-dermotenzii-v-pervuyu-fazu-ranevogo-protsessa

6. Lee JW, Park SH, Lee SJ, et al. New economical and simple device for intraoperative expansion on small and medium sized soft tissue defects. Arch Craniofac Surg. 2018;1(3):235-239.

7. Ilizarov GA, Shurov VA. The effect of tension on the biomechanical properties of muscles, their blood supply and leg growth. Human physiology. 1988;14(1):26-32. (In Russ.)

8. Ivashkov VYu, Gorbacheva OYu, Azimova RB, Sobolevsky VA. Options for replacing extensive defects of the anterior abdominal wall in malignant neoplasms of the skin and soft tissues. Bone and soft tissue sarcomas and skin tumors. 2016;4:40-48. (In Russ.)

9. Izmailov SG, Izmailov GA, Reznik VS, et al. Adaptation-repositioning technical means in combination with the bioactive pharmacological drug xymedon for stimulation of wound healing. Medical equipment. 1999;2:16-23. (In Russ.)

10. Izmaylov SG, Izmaylov GA. Novye tekhnologii v khirurgii ran: monografiya. Izd-vo NGMA; 2004. (In Russ.)

11. Izmailov SG, Lukoyanychev EE, Izmailov AG, Izmailov AA, Rotkov AI. Technical means of joining wound edges. Bulletin of the Pirogov National Medical and Surgical Center. 2023;18(1):145-152. (In Russ.)

12. Bjarnesen JP, Wester JU, Siemssen SS, Blomqvist G, Jensen NK. External tissue stretching for closing skin defects in 22 patients. Acta Orthop Scand. 1996;67(2):182-184.

13. Ger R. The use of external tissue expansion in the management of wounds and ulcers. Ann Plast Surg. 1997;38(4):352-357.

14. Song M, Zhang Z, Liu T, et al. EASApprox® skin-stretching system: A secure and effective method to achieve wound closure. Exp Ther Med. 2017;14(1):531-538.

15. Guo H, Tang J, Zhang J, et al. Effectiveness analysis of disposable skin stretch closure in treatment of difficult to close skin and soft tissue defects. Chin J Reparative Reconstr Surg. 2022;36(6):760-765.

16. Fang Y, Qiu J, Yu S, Wang Y. A new clip-type nailing device for rapid wound closure and hemostasis. Asian J Surg. 2024;47(4):1803-1804.

17. Govaert GA, van Helden S. Ty-raps in trauma: a novel closing technique of extremity fasciotomy wounds. J Trauma. 2010;69(4):972-975.

18. Svetukhin AM, Amiraslanov YuA, Mitish VA. Rekonstruktivnye i plasticheskie operatsii v gnoynoy khirurgii. V kn.: Fedorov VD, Svetukhina AM. Izbrannyy kurs lektsiy po gnoynoy khirurgii. Miklosh; 2005:64-76. (In Russ.)

19. Amiraslanov YuA, Sarkisov DS, Kolokolchikova EG. Plastic surgery of soft tissue defects using the dosed tissue stretching method. Doctor. 1993;2:25-27. (In Russ.)

20. Igoumenou VG, Kokkalis ZT, Mavrogenis AF. Fasciotomy wound management. In: Mauffrey C, Hak DJ, Martin III MP, eds. Compartment Syndrome: A Guide to Diagnosis and Management. 2019:83-95.

21. Alkhalifah MK, Almutairi FSH. Optimising wound closure following a fasciotomy: A narrative review. Sultan Qaboos Univ Med J. 2019;19(3):e192-e200.

22. Yontar Y, Tatar S, Aydin A, Coruh A. Delayed primary closure of traumatic tension wounds using plastic straps and Kirschner wires. Plast Surg (Oakville). 2019;27(1):29-37.

23. Miroshnichenko VO, Kabanov MYu, Semenov KV, et al. Use of various tension techniques in the formation of a short leg stump after a mine-blast wound. Bulletin of the Pirogov National Medical and Surgical Center. 2024;19(4):174–177. (In Russ.)

24. Choudhary AN, Kumar S. Cable ties: Poor man's top closure system. Indian J Plast Surg. 2023;56(2):182-184.

25. Cohen BH, Cosmetto AJ. The suture tension adjustment reel. A new device for the management of skin closure. J Dermatol Surg Oncol. 1992;18(2):112-123.

26. Dodenhoff RM, Howell GE. The shoelace technique for wound closure in open fractures: report of early experience. Injury. 1997;28(9-10):593-595.

27. Lee ET. A new wound closure achieving and maintaining device using serial tightening of loop suture and its clinical applications in 15 consecutive patients for up to 102 days. Ann Plast Surg. 2004;53(5):436-441.

28. Medina C, Spears J, Mitra A. The use of an innovative device for wound closure after upper extremity fasciotomy. Hand (N Y). 2008;3(2):146-151.

29. Topaz M, Carmel NN, Silberman A, Li M Sen, Li YZ. The TopClosure® 3S System, for skin stretching and a secure wound closure. Eur J Plast Surg. 2012;35(7):533-543.

30. Li J, Shi JB, Hong P, et al. Combined treatment with vacuum sealing drainage, TopClosure device, and Ilizarov technique for traumatic hemipelvectomy: A rare case report of successful repairing of large-size soft tissue defects. Medicine (Baltimore). 2019;98(4):e14205.

31. Pintor-Tortolero J, Sánchez-Arteaga A, Tallón-Aguilar L, Padillo-Ruiz FJ. Fasciotomy wound secondary to necrotizing fasciitis closure using combination of negative pressure wound therapy and progressive primary closure. ANZ J Surg. 2019;89(1-2):E49.

32. Dekker PK, Chang BL, Fleury CM, Evans KK. Retention sutures and negative pressure wound therapy for delayed primary closure of fasciotomy wounds. Plast Reconstr Surg Glob Open. 2021;9(4):e3530.

33. Pan Y, Deng Y, Hu C, Zhu K, Feng C. Application of suture-stretching technique in repairing skin defect of lower limb. J Orthop Surg Res. 2025;20:46.

34. Wang L, Wang C, Chen H, et al. The combined use of a non-invasive skin-stretching device and the negative-pressure wound therapy technique in the treatment of postoperative diabetic foot. Diabetes Metab Syndr Obes. 2021;14:3523-3532.

35. Pyatakov SN, Porkhanov VA, Zavrazhnov AA, et al. Evaluation of the clinical efficacy of the dosed tissue stretching method in the treatment of skin and tissue defects in the abdominal wall area. TMBV. 2018;2. (In Russ.) URL: https://cyberleninka.ru/article/n/otsenka-klinicheskoy-effektivnosti-primeneniya-metoda-dozirovannogo-tkanevogo-rastyazheniya-v-lechenii-defektov-kozhi-itkaney-v

36. Barnea Y, Gur E, Amir A, et al. Delayed primary closure of fasciotomy wounds with Wisebands, a skin- and soft tissue-stretch device. Injury. 2006;37(6):561-566.

37. Barnea Y, Gur E, Amir A, et al. Our experience with Wisebands: a new skin and soft-tissue stretch device. Plast Reconstr Surg. 2004;113(3):862-869.

38. Oh SJ. Closure of a full-thickness scalp burn that occurred during hair coloring using a simple skin-stretching method: A case report and review of the literature. Arch Plast Surg. 2019;46(2):167-170.

39. Taylor RC, Reitsma BJ, Sarazin S, Bell MG. Early results using a dynamic method for delayed primary closure of fasciotomy wounds. J Am Coll Surg. 2003;197(5):872-878.

40. May BL, Googe B, Durr S, et al. Utility of a continuous external tissue expander in complex pediatric wound reconstruction. Eplasty. 2022;22:e10.

41. MacKay BJ, Dardano AN, Klapper AM, et al. Multidisciplinary application of an external tissue expander device to improve patient outcomes: A critical review. Adv Wound Care. 2020;9(9):525-538.

42. Pyatakov SN, Baryshev AG, Mukhanov ML, et al. A case of successful use of a new device for dosed stretching of soft tissues in the treatment of a victim with an extensive post-traumatic wound defect of the lower leg. Polytrauma. 2024;3:84-89. (In Russ.)

43. Cheng LF, Lee JT, Hsu H, Wu MS. Simple skin-stretching device in assisted tension-free wound closure. Ann Plast Surg. 2017;78(3 Suppl 2):S52-S57.

44. Chen Q, Su W. Treatment of 16 cases of skin defect by stretch regeneration according to law of tension stress. Chin J Orthopaedic Trauma. 2018;20:537-540.

45. Xu J, Chang R, Zhang W, et al. Skin stretch suturing with Nice knots in the treatment of small- or medium-sized wounds. J Orthop Surg Res. 2020;15(1):488.

46. Izmailov GA, Akhmetzyanov SHI, Izmailov SG. Device for bringing wound edges together. Surgery. 1984;12:106-109. (In Russ.)

47. Ismailov GA, Ismailov SG. Apparative adaptation der wundränder. Chrurgische Prax. 1997;52(H3):425-430.

48. Armstrong DG, Sorensen JC, Bushman TR. Exploiting the viscoelastic properties of pedal skin with the Sure Closure skin stretching device. J Foot Ankle Surg. 1995;34(3):247-253.

49. Kocialkowski A, Marsh DR, Shackley DC. Closure of the skin defect overlying infected non-union by skin traction. Br J Plast Surg. 1998;51(4):307-310.

50. Ren G, Zhang M, Cui Z, Wang G, Yu B. Skin stretching device combined with collagen sponge for wound repair. Chin J Orthopaedic Trauma. 2018;20:689-695.

51. Wu Q, Shao Z, Li Y, et al. A novel skin-stretching device for closing large skin-soft tissue defects after soft tissue sarcoma resection. World J Surg Oncol. 2020;18(1):247.

52. Dong Q, Gu G, Wang L, et al. Application of modified adjustable skin stretching and secure wound-closure system in repairing of skin and soft tissue defect. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2017;31(12):1481-1484.

53. Harvey RJ, Litwak P, Ribich W, Dbowik J. Wound closing device. US Patent No. 4430998; 1984. 54 Zhu Y, Pan S, Xu Y, et al. The efficacy of modified Ilizarov distraction-tension device on limb wound difficult to cover with skin flaps. Orthop Surg. 2024;16(9):2221-2229.

54. Pyatakov SN, Porkhanov VA, Zavrazhnov AA, et al. Evaluation of the clinical efficacy of the dosed tissue stretching method in the treatment of skin and tissue defects in the abdominal wall area. TMBV. 2018;2. (In Russ.) URL: https://cyberleninka.ru/article/n/otsenkaklinicheskoy-effektivnosti-primeneniya-metoda-dozirovannogo-tkanevogo-rastyazheniya-v-lechenii-defektov-kozhi-i-tkaney-v

55. Alekseev AA, Bobrovnikov AE, Malyutina NB, Avagimyan AG. Experience of clinical use of URGO dressings. Combustiology. 2009;39. (In Russ.)

56. Risnes I, Abdelnoor M, Lundblad R, et al. Leg wound closure after saphenous vein harvesting in patients undergoing coronary artery bypass grafting: a prospective randomized study comparing intracutaneous, transcutaneous and zipper techniques. Scand Cardiovasc J. 2002;36(6):378-382.

57. Wang L, Wang C, Chen H, et al. Application of noninvasive skin-stretching device in wound healing of diabetic foot. Chin J Diabetes Mellitus. 2018;10:729-734.

58. Kerrigan CL, Homa K. Evaluation of a new wound closure device for linear surgical incisions: 3M Steri-Strip S surgical skin closure versus subcuticular closure. Plast Reconstr Surg. 2010;125(1):186-194.

59. Doumit J, Vale R, Kanigsberg N. Dynaclose tape: a practical alternative to punch biopsy site closure. J Cutan Med Surg. 2013;17(1):62-65.

60. Izmailov SG, Ryabkov MG, Leontyev AE, et al. Use of adaptive instruments in surgery of relaparotomy wounds. Kazan Medical Journal. 2019;2:351–357. (In Russ.)

61. Izmaylov SG, Rotkov AI, Beschastnov VV, et al. Mathematical justification of the wound suturing by wound contractors of new generation. In: Phys Technol Proc (CPT2020) Conf Proc 8th Int Sci Conf Comput. 2020:232-238.

62. Izmailov SG, Beschatnov VV, Garaev VN, et al. New directions in surgical technologies for the treatment of soft tissue wounds. Bulletin of the Russian Academy of Medical Sciences. 2005;10:25-30. (In Russ.)

63. Beschatnov VV, Orlinskaya NYu, Kudykin MN. Experimental and clinical evaluation of the possibility of dosed dermotension in conditions of an infected soft tissue wound. Russian Medical Journal. 2012;3:32-34. (In Russ.)

64. Virág TH, Muntean MV, Mihály AZ, Georgescu AV. Experimental investigation of tension-reducing effectiveness of keystone perforator island flap. Med Pharm Rep. 2024;97(2):196-204.

65. Scheepens KMJ, Marsidi N, Genders RE, Horeman-Franse T. The compressiometer: Toward a new skin tensiometer for research and surgical planning. IEEE J Transl Eng Health Med. 2021;10:2500109.

66. Lackmann F, Rohwedder T, Maron A, et al. Quantification of skin wound tension using a newly designed wound tensiometer. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2023;51(6):386-393.


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Kabanov M.Yu., Glushkov N.I., Miroshnichenko V.O., Gorshenin T.L., Binienko M.A., Izmaylov S.G., Bogdanov S.N. Current approaches to surgical treatment of soft tissue defects using tissue expansion techniques. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2025;15(5):69-77. (In Russ.) https://doi.org/10.20340/vmi-rvz.2025.5.CLIN.6

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ISSN 2226-762X (Print)
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