FULMINANT ACUTE PANCREATITIS: HOW TO IMPROVE SURGICAL OUTCOMES IN THE PHASE OF ENZYMATIC TOXEMIA
Abstract
In patients with progressive severe acute pancreatitis (SAP), early surgery is the last opportunity to influence the dismal outcome. The use of extracorporeal detoxification (ECD) methods along with a traditional surgical approach does not improve the outcomes of early surgeries in patients with progressive SAP due to the late elimination of aggression factors, as well as due to constant reabsorption of enzymatic toxic exudate from non-drained areas of the retroperitoneal space, abdominal cavity, and omentum. Preventive use of ECD (plasma exchange) can improve the outcomes of early surgeries in patients with fulminant SAP.
About the Authors
E. A. Korymasov
Federal State Budgetary Institution of Higher Education ‘Samara State Medical University’, Ministry of Health of the Russian Federation
Russian Federation
Samara
Russian Federation
Samara
M. Yu. Khoroshilov
Federal State Budgetary Institution of Higher Education ‘Samara State Medical University’, Ministry of Health of the Russian Federation
Russian Federation
Samara
Russian Federation
Samara
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Review
For citations:
Korymasov E.A., Khoroshilov M.Yu. FULMINANT ACUTE PANCREATITIS: HOW TO IMPROVE SURGICAL OUTCOMES IN THE PHASE OF ENZYMATIC TOXEMIA. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2020;(3):62-67. (In Russ.)
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