Multidisciplinary approach in the treatment of a victim with severe combined trauma complicated by massive blood loss to soft tissues (clinical case)
https://doi.org/10.20340/vmi-rvz.2024.2.CASE.2
Abstract
Using the example of clinical observation, the features of withdrawal from shock, the possibility of using hemofiltration in the early stages after severe combined trauma complicated by blood loss to soft tissues, which made it possible to avoid the development of infectious complications, are shown.
About the Authors
E. S. VladimirovaElizaveta S. Vladimirova, Dr. Sci. (Med.), Scientific consultant of the Department of Emergency Surgery
3, Bolshaya Sukharevskaya pl., Moscow, 129090
F. A. Chernousov
Fedor A. Chernousov, Dr. Sci. (Med.), Professor, Senior Researcher at the Department of Emergency Surgery
3, Bolshaya Sukharevskaya pl., Moscow, 129090
P. A. Ivanov
Pavel A. Ivanov, Dr. Sci. (Med.), Head of the Scientific Department of Combined and Multiple Trauma
3, Bolshaya Sukharevskaya pl., Moscow, 129090
S. A. Badygov
Stanislav A. Badygov, Head of the Intensive Care Unit for Emergency Patients
3, Bolshaya Sukharevskaya pl., Moscow, 129090
S. I. Rey
Sergey I. Rey, Cand. Sci. (Med.), Senior Research Officer of Emergency Surgery Department
3, Bolshaya Sukharevskaya pl., Moscow, 129090
G. A. Berdnikov
Gennadiy A. Berdnikov, Cand. Sci. (Med.), Senior Research Officer of Emergency Surgery Department
3, Bolshaya Sukharevskaya pl., Moscow, 129090
E. V. Klychnikova
Elena V. Klychnikova, Cand. Sci. (Med.), Head of the Scientific Department of the Clinical and Biochemical Laboratory of Emergency Research Methods
3, Bolshaya Sukharevskaya pl., Moscow, 129090
O. A. Alekseechkina
Ol'ga A. Alekseechkina, Cand. Sci. (Med.), Senior Research at the Department of Radiation Diagnostics
3, Bolshaya Sukharevskaya pl., Moscow, 129090
I. E. Popova
Russian Federation
Irina E. Popova, Cand. Sci. (Med.), Senior Research at the Department of Radiation Diagnostics
3, Bolshaya Sukharevskaya pl., Moscow, 129090
References
1. Wafaisade A, Lefering R, Bouillon B, Sakka SG, Thamm OC, Paffrath T, et al.; Trauma Registry of the German Society for Trauma Surgery. Epidemiology and factors of sepsis after multiple trauma: an analysis of 29, 829 patients from the Trauma Registry of German Society for Trauma Surgery. Crit Care Med. 2011;39(4):621-628. PMID: 21242798 https://doi.org/10.1097/CCM.0b013e318206d3df
2. AlRawahi AN, AlHinai FA, Doig CJ, Ball CG, Dixon E, Xiao Z, et al. The prognostic value of serum procalcitonin measurements in critically injured patients: a systematic review. Crit Care. 2019;23(1):390. PMID: 31796098 https://doi.org/10.1186/s13054-019-2669-1
3. Honore PM, David C, Attou R, Redant S, Gallerani A, De Bels D. Procalcitonin to allow early detection of sepsis and multiple organ failure in severe multiple trauma: beware of some confounders. Crit Care. 2020;24(1):9. PMID: 31910884 https://doi.org/10.1186/s13054-020-2729-6
4. Vladimirova ES, Ivanov PA, Badigov SA, Popova IE, Rey SI, Alekseechkina OA, et al. Prognosis, Early Diagnosis and Treatment of Multiple Organ Failure in a Patient With Severe Concomitant Trauma. Russian Sklifosovsky Journal of Emergency Medical Care. 2022;11(4):708–717. https://doi.org/10.23934/2223-9022-2022-11-4-708-717 (in Russ.)
5. van Wessem KJP, Leenen LPH. Reduction in mortality rates of postinjury multiple organ dysfunction syndrome: a shifting paradigm? a prospective population-based cohort study. Shock. 2018;49(1):33–38. PMID: 28682941 https://doi.org/10.1097/SHK.0000000000000938
6. Bulava GV. Pathogenetic Mechanisms of Organ Dysfunction in Severe Concomitant Trauma. Russian Sklifosovsky Journal "Emergency Medical Care". 2023;12(1):92-98. (In Russ.)] https://doi.org/10.23934/2223-9022-2023-12-1-92-98
7. Kishikawa T, Fujieda H, Sakaguchi H. Comprehensive analysis of cytokine adsorption properties of polymethyl methacrylate (PMMA) membrane material. J Artif Organs. 2022;25(4):343-349. PMID: 35301606 https://doi.org/10.1007/s10047-022-01323-6
8. Takala A, Jousela I, Jansson SE, Olkkola KT, Takkunen O, Orpana A, et al. Markers of systemic inflammation predicting organ failure in community-acquired septic shock. Clin Sci (London). 1999;97(5):529-538. PMID: 10545303 https://doi.org/10.1042/cs0970529
9. Takeda K. Evolution and integration of innate immune recognition systems: The Toll-like receptors. J Endotoxin Res. 2005;11(1):51-55. PMID: 15826379 https://doi.org/10.1179/096805105225006687
10. Howard BM, Kornblith LZ, Christie SA, Conroy AS, Nelson MF, Campion EM, et al. Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury. Trauma Surg Acute Care Open. 2017;2(1):e000108. PMID: 29766103 https://doi.org/10.1136/tsaco-2017-000108
11. Putzu A, Schorer R, Lopez-Delgado JC, Cassina T, Landoni G. Blood Purification and Mortality in Sepsis and Septic Shock a Systematic Review and Metaanalysis of Randomized Trials. Anesthesiology. 2019;131(3):580-593. PMID: 31246600 https://doi.org/10.1097/ALN.0000000000002820
12. Snow TAC, Littlewood S, Corredor C, Singer M, Arulkumaran N. Effect of Extracorporeal Blood Purification on Mortality in Sepsis: a Meta-Analysis and Trial Sequential Analysis. Blood Purif. 2021;50(4-5):462-472. PMID: 33113533 https://doi.org/10.1159/000510982
13. Chen JY, Chen YY, Pan HC, Hsieh CC, Hsu TW, Huang YT, et al. Accelerated versus watchful waiting strategy of kidney replacement therapy for acute kidney injury: a systematic review and meta-analysis of randomized clinical trials. Clin Kidney J. 2022;15(5):974–984. PMID: 35498901 https://doi.org/10.1093/ckj/sfac011
14. Gaudry S, Hajage D, Martin-Lefevre L, Lebbah S, Louis G, Moschietto S, et al. Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial. Lancet. 2021;397(10281):1293-1300. PMID: 33812488 https://doi.org/10.1016/S0140-6736(21)00350-0
15.
Supplementary files
Review
For citations:
Vladimirova E.S., Chernousov F.A., Ivanov P.A., Badygov S.A., Rey S.I., Berdnikov G.A., Klychnikova E.V., Alekseechkina O.A., Popova I.E. Multidisciplinary approach in the treatment of a victim with severe combined trauma complicated by massive blood loss to soft tissues (clinical case). Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2024;14(2):86-96. (In Russ.) https://doi.org/10.20340/vmi-rvz.2024.2.CASE.2