TREATMENT STRATEGY FOR FULMINANT ACUTE PANCREATITIS AFTER ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY
Abstract
The incidence of complications after endoscopic retrograde cholangiopancreatography (ERCP) is reported to be 1% to 15% [4]. Acute post-intervention pancreatitis is a serious complication after endoscopic transpapillary procedures; it is characterized by rapid progression and high mortality rates [8]. In up to 15% of patients, severe acute post-intervention pancreatitis is accompanied by pancreatic necrosis and multiple organ failure [4]. The death rate in sterile pancreatic necrosis varies between 15% and 30%, whereas in infective pancreatic necrosis, the death rate reaches 85% [3, 9]. Intraductal pancreatic hypertension has a crucial importance in the pathogenesis of acute pancreatitis; therefore, early and adequate decompression minimizes the risk of severe parapancreatic complications [1]. Preventive stenting of the main pancreatic duct (MPD) significantly reduced the risk of this complication. However, there is still no consensus on the effectiveness of this preventive measure [7]. The accumulation of collective experience will allow us to develop a unified strategy for patients at risk of acute post-intervention pancreatitis.
About the Authors
E. A. Korymasov
Federal State Budgetary Institution of Higher Education ‘Samara State Medical University,’ Ministry of Health of the Russian Federation
Russian Federation
Samara
Russian Federation
Samara
A. V. Zhdanov
Federal State Budgetary Institution of Higher Education ‘Samara State Medical University,’ Ministry of Health of the Russian Federation
Russian Federation
Samara
Russian Federation
Samara
M. Yu. Khoroshilov
Federal State Budgetary Institution of Higher Education ‘Samara State Medical University,’ Ministry of Health of the Russian Federation
Russian Federation
Samara
Russian Federation
Samara
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Review
For citations:
Korymasov E.A., Zhdanov A.V., Khoroshilov M.Yu. TREATMENT STRATEGY FOR FULMINANT ACUTE PANCREATITIS AFTER ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2020;(2):27-31. (In Russ.)
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