Morphological diagnosis of nontuberculous mycobacteriosis in the surgical material of patients with pulmonary tuberculosis
https://doi.org/10.20340/vmi-rvz.2023.2.MORPH.2
Abstract
Objective: to analyze the results of a morphological study of the lung tissue and small airways in the surgical material of patients with a combination of tuberculoma and nontuberculous mycobacteriosis of the lungs caused by different types of pathogen.
Materials and methods. A comparative retrospective histological study of the surgical material of 34 patients with a combination of LT and NM with established microbiological different types of non-tuberculous mycobacteria (NTMB) and 36 patients with LT without concomitant pathology was carried out.
Results. Diagnostically significant differences in the morphological picture of TL and NM, which manifests its morphological features in areas free from foci of tuberculosis, were revealed. The features of changes in the lung tissue and small airways in patients with slow- and fast-growing types of NTMB are shown.
Conclusion. The results obtained are aimed at resolving the issue of possible correction of chemotherapy in the postoperative period.
About the Authors
L. N. Lepekha
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Larisa N. Lepekha, Dr. Sci. (Med.), Professor, Chief Researcher of the Department of Pathomorphology, Cell Biology and Biochemistry,
2 Yauzskaya alley, Moscow, 107564
E. V. Krasnikova
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Elena V. Krasnikova, Dr. Sci. (Med.), Thoracic Surgeon, Head of the Second Surgical Department, Central Research Institute of Tuberculosis,
2 Yauzskaya alley, Moscow, 107564
R. V. Tarasov
Central Tuberculosis Research Institute;
Moscow Medical University "Reaviz"
Russian Federation
Russian Federation
Ruslan V. Tarasov, surgeon, Junior Researcher, Department of Surgery, 2 Yauzskaya alley, Moscow, 107564;
asistant of the Department of Surgical Diseases, 2, building 2 Krasnobogatyrskaya, Moscow, 107564
S. S. Nikitin
Central Tuberculosis Research Institute
Russian Federation
Russian Federation
Sergey S. Nikitin, Research Laboratory Assistant, Department of Pathomorphology, Cell Biology and Biochemistry,
2 Yauzskaya alley, Moscow, 107564
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For citations:
Lepekha L.N., Krasnikova E.V., Tarasov R.V., Nikitin S.S. Morphological diagnosis of nontuberculous mycobacteriosis in the surgical material of patients with pulmonary tuberculosis. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2023;13(2):16-22. (In Russ.) https://doi.org/10.20340/vmi-rvz.2023.2.MORPH.2
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