Preview

Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)

Advanced search

Evolution of cavity formation in nontuberculosis mycobacteriosis of the lungs

https://doi.org/10.20340/vmi-rvz.2023.5.CASE.4

Abstract

The results of a long – term observation from practice are presented, which showed the gradual formation of the destruction cavity in a patient with limited focal and peribronchial fibrosis of the lung tissue. Patient H., 54 years old for more than twenty years, was observed by a pulmonologist at the place of residence with a diagnosis of chronic bronchitis with frequent annual exacerbations. She was admitted to the clinic of the FSBSI "CRIT" with complaints of pronounced weakness, fatigue, shortness of breath, prolonged subfebrile temperature mainly at night, cough with difficult-to-separate mucus of a mucous nature. A retrospective analysis of computed tomography of the chest revealed a consistent transformation of local focal peribronchial compaction in the middle lobe of the right lung into a limited area of bronchiectasia and the formation of a small cystic cavity with widespread zones of bilateral pneumonic infiltration. This observation shows the practical significance of CT research in understanding the mechanisms of formation of bronchiectatic cystic cavity in non-tuberculosis mycobacteriosis of the lungs.

About the Authors

R. B. Amansakhedov
Central Research Institute of Tuberculosis
Russian Federation

Rasul B. Amansakhedov - Doctor of Medical Sciences, leading researcher,

2 Yauzskaya Alley, 2, Moscow, 107564



N. N. Makar'yants
Central Research Institute of Tuberculosis
Russian Federation

Natal'ya N. Makar'yants - Doctor of Medical Sciences, Leading researcher, Head of the Department of Differential Diagnosis of Pulmonary Tuberculosis and extra-corporeal methods of treatment,

2 Yauzskaya Alley, 2, Moscow, 107564



A. Yu. Borisova
Central Research Institute of Tuberculosis

Anastasiya Y. Borisova - Radiologist,

2 Yauzskaya Alley, 2, Moscow, 107564



U. V. Belova
Central Research Institute of Tuberculosis
Russian Federation

Ul'yana V. Belova - Radiologist,

2 Yauzskaya Alley, 2, Moscow, 107564



L. N. Lepekha
Central Research Institute of Tuberculosis
Russian Federation

Larisa N. Lepekha - Dr. Sci. (Med.), Professor, Chief Researcher of the Department of Pathomorphology, Cell Biology and Biochemistry,

2 Yauzskaya Alley, 2, Moscow, 107564



N. L. Karpina
Central Research Institute of Tuberculosis
Russian Federation

Natal'ya L. Karpina - Doctor of Medical Sciences, Deputy Director for Scientific Work, Head of the Center for Diagnosis and Rehabilitation of Respiratory Diseases,

2 Yauzskaya Alley, 2, Moscow, 107564



References

1. 1 Cole PJ. Inflammation: a two-edged sword – the model of bronchiectasis. European Journal of Respiratory Diseases. Supplement. 1986; 147:6-15.

2. 2 Nontuberculosis mycobacteria, mycobacterioses. Edited by V.I. Litvinov, E.M. Bogorodskaya, S.E. Borisov. Moscow: MNPTSBT. 2014:256. (In Russ).

3. 3 Moore E.H. Atypical mycobacterial infection in the lung: CT appearance. Radiology. 1993;187:777-782. https://doi.org/10.1148/radiology.187.3.8497629.

4. 4 Tanaka E., Amitano R, Kuze F. Clinical features of the patients with "secondary infection" of Mycobacterium avium complex-Radiographic pattern of progressions in the patients with and without underlying pulmonary conditions. Kekkaku. 1993 Jan;68(1):57-61.

5. 5 Kimberly To. et al. General Overview of Nontuberculous Mycobacteria Opportunistic Pathogens: Mycobacterium avium and Mycobacterium abscessus. J. Clin. Med. 2020;9(8):2541. https://doi.org/10.3390/jcm9082541

6. 6 Tae Sung Kim, Won-Jung Koh, Joungho Han et al. Hypothesis on the Evolution of Cavitary Lesions in Nontuberculous Mycobacterial Pulmonary Infection: Thin-Section CT and Histopathologic Correlation. AJR. 2005;184:1247-1252.

7. 7 Milliron B. et al. Bronchiectasis: mechanisms and Imaging of Associated Common and Uncommon Diseases RadioGraphics. 2015;35:1011-1030. https://doi.org/10.1148/rg.2015140214

8. 8 Lepekha L.N., Amansakhedov R.B., Makaryants N.N., et al. Structural and functional characteristics of bronchiolitis caused by fast-growing strains of non-tuberculosis mycobacteria. Bulletin of the Central Research Institute. 2023;7(1):40-51. https://doi.org/10.57014/2587-6678-2023-7-1-40-51 (In Russ).


Supplementary files

Review

For citations:


Amansakhedov R.B., Makar'yants N.N., Borisova A.Yu., Belova U.V., Lepekha L.N., Karpina N.L. Evolution of cavity formation in nontuberculosis mycobacteriosis of the lungs. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH). 2023;13(5):137-141. (In Russ.) https://doi.org/10.20340/vmi-rvz.2023.5.CASE.4

Views: 262


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2226-762X (Print)
ISSN 2782-1579 (Online)